CAS NO:89226-50-6 ...

CAS NO:89226-50-6 Manidipine
CAS NO:89226-50-6 Manidipine
CAS NO:89226-50-6 Manidipine

CAS NO:89226-50-6 Manidipine

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Keywords

Manidipine 89226-50-6 C35H38N4O6

Quick Details

  • Appearance:powder
  • Application:89226-50-6
  • PackAge:as requested
  • ProductionCapacity:300|Kilogram|Month
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Manidipine Basic information
Product Name: Manidipine
Synonyms: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl Methyl Ester;MANIDIPINE: MANIDIPINE DIHYDROCHLORIDE;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester (9CI);Franidipine;Manidipine 6300;1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-[2-[4-(diphenylmethyl)-1-piperazinyl]ethyl] ester;1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 5-methyl 3-[2-[4-(diphenylmethyl)-1-piperazinyl]ethyl] ester;1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-[2-[4-(diphenylmethyl)piperazin-1-yl]ethyl]5-methyl ester
CAS: 89226-50-6
MF: C35H38N4O6
MW: 610.7
EINECS:  
Product Categories: Dihydropyridine Class Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Dihydropyridine;Artedil, Iperten;Inhibitors
Mol File: 89226-50-6.mol
Manidipine Structure
 
Manidipine Chemical Properties
Melting point  125-128°C
storage temp.  -20°C Freezer
 
Safety Information
MSDS Information
 
 
Manidipine Usage And Synthesis
Chemical Properties Light Yellow Crystalline Solid
Usage A dihydropyridine calcium channel blocker. Antihypertensive
Usage Manidipine (Manyper) is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM. It causes systemic vasodilation by inhibiting the voltage-dependent calcium inward currents in smooth muscle cells. It
 
Manidipine Preparation Products And Raw materials
Raw materials Magnesium sulfate-->Isopropyl ether-->Acetyl ketene-->Methyl 3-aminocrotonate-->N-(2-Hydroxyethyl)piperazine-->Manidipine hydrochloride-->Manidipine

 

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