JW55

JW55
JW55
JW55

JW55

Min.Order / FOB Price:Get Latest Price

1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 98%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

JW55 664993-53-7 C25H26N2O5

Quick Details

  • Appearance:powder
  • Application:664993-53-7
  • PackAge:as requested
  • ProductionCapacity:300|Kilogram|Month
  • Storage:store in cool, dry place
  • Transportation:by sea or by air

Superiority:

JW55 Basic information
Product Name: JW55
Synonyms: JW55;N-(4-((4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)MethylcarbaMoyl)phenyl)furan-2-carboxaMide;N-[4-[[[[Tetrahydro-4-(4-methoxyphenyl)-2H-pyran-4-yl]methyl]amino]carbonyl]phenyl]-2-furancarboxamide;JW55 N-[4-[[[[Tetrahydro-4-(4-methoxyphenyl)-2H-pyran-4-yl]methyl]amino]carbonyl]phenyl]-2-furancarboxamide;JW 55, >=98%
CAS: 664993-53-7
MF: C25H26N2O5
MW: 434.48434
EINECS: -0
Product Categories: Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors
Mol File: 664993-53-7.mol
JW55 Structure
 
JW55 Chemical Properties
storage temp.  2-8°C
 
Safety Information
MSDS Information
 
 
JW55 Usage And Synthesis
Usage JW-55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). Activity results in stabilization of Axin2 and increased degradation of β-catenin. JW-55 inhibits the β-catenin signaling pathway. Also shown to decrease canonical Wnt signaling in SW480 and HCT-15 colon carcinoma cell lines. JW-55 reduces cell cycle progression and proliferation in SW480 cells in vitro.
 
JW55 Preparation Products And Raw materials

 

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