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Peptides Pharmaceutical Intermediate Chemical
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Description
1.Product Name : Salmon Calcitonin // CAS 47931-85-1
2.Appearance : White powder
3.Specification : 95% ,98% ,99%
4.Introduction :
Calcitonin is a 32-amino acid linear polypeptide hormone that is produced in humans primarily by the parafollicular cells (also known as C-cells) of thethyroid, and in many other animals in the ultimobranchial body.It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH).
Description
Calcitonin (salmon) is an hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Calcitonin decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes. Calcitonin contains a single disulfide bond, which causes the amino terminus to assume the shape of a ring. Alternative splicing of the calcitonin pre-mRNA can yield a mRNA encoding calcitonin gene-related peptide; that peptide appears to function in the nervous and vascular systems. The calcitonin receptor has been cloned and shown to be a member of the seven-transmembrane, G protein-coupled receptor family.
Specification
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