Peptide Bivalirudin Trifluoroacetate

Details:

Peptide Bivalirudin Trifluoroacetate 

Molecular Formula：

C₉₈H₁₃₈N₂₄O₃₃

Relative Molecular Mass：

2180.32 g/mol

CAS-Number：

128270-60-0 (net)

Long-term Storage：

-20 ± 5 °C

Synonyms：

BG 8967; Hirulog; Hirulog I

Sequence：

H-D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH trifluoroacetate salt

Fields of Application：

Moderate to high risk acute coronary syndromes

Percutaneous coronary intervention

Active Substance：

Bivalirudin is a synthetic hirudin analog. Bivalirudin acts as a specific and reversible direct thrombin inhibitor.

------Product Description------

Bivalirudin is a new synthetic anticoagulant, thrombin direct, specific, reversible inhibitor. Initially developed by the Swiss company of Biogen (Biogen) successfully transferred to the United States after the MedicinesCompany, approved in 2000 in the United States. Its anticoagulant component is a hirudin-derived 20-peptide compound. Whether thrombin in the blood circulation, or thrombin-bound thrombin, bivalirudin can be combined with its catalytic site and anionic binding sites of specific binding, thereby inhibiting the activity of thrombin directly, and its role is characterized by a brief ,reversible. Early clinical studies have shown that anticoagulant therapy with bivalirudin is more effective and has a lower incidence of bleeding events and is safer than conventional heparin anticoagulation. Mainly for the prevention of angioplasty interventional treatment of unstable angina before and after ischemic complications.

-----Company Info------ 

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