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(αR)-3-(AMinoiMinoMethyl)-α-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]aMino]ethyl]benzenepropanoic Acid Methyl Ester 193153-04-7 supplier 193153-04-7 price
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Methyl (2R,3R)-2-[3-amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate Basic information |
Product Name: | Methyl (2R,3R)-2-[3-amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate |
Synonyms: | Methyl (2R,3R)-2-[3-amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate;(αR)-3-(AMinoiMinoMethyl)-α-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]aMino]ethyl]benzenepropanoic Acid Methyl Ester;[R-(R*,R*)]-3-(AMinoiMinoMethyl)-α-[1-[[4-(1-oxido-4-pyridinyl)benzoyl]aMino]ethyl]benzenepropanoic Acid Methyl Ester;FXV 673;Methyl (2R,3R)-2-{3-[aMino(iMino)Methyl]benzyl}-3-{[4-(1-oxidopyridin-4-yl)benzoyl]aMino}butanoate;Preluent;OtaMixaban (FXV 673);FXV673/FXV-673 |
CAS: | 193153-04-7 |
MF: | C25H26N4O4 |
MW: | 447.50628 |
EINECS: | |
Product Categories: | Amines;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals |
Mol File: | 193153-04-7.mol |
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Methyl (2R,3R)-2-[3-amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate Chemical Properties |
density | 1.25 |
Safety Information |
Methyl (2R,3R)-2-[3-amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate Usage And Synthesis |
Usage | A potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. Clinical studies show that it is efficacious , safe and well tolerated in humans and therefore has considerable potential for the treatment of acute coronary syndrome. |