24-CYCLOPROPYL-(1ALPHA,3BETA,5Z,7E,22E,24S)-9,10-SECOCHOLA-5,7,10(19),22-TETRAENE-1,3,24-TRIOL 112965-21-6 supplier 112965-21-6 price
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Calcipotriene Basic information |
Product Name: | Calcipotriene |
Synonyms: | 24-CYCLOPROPYL-(1ALPHA,3BETA,5Z,7E,22E,24S)-9,10-SECOCHOLA-5,7,10(19),22-TETRAENE-1,3,24-TRIOL;5z,7e,22e,24s)--bet;9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol,24-cyclopropyl-,(1-alpha,3;dovonex;mc903;CALCIPOTRIOL,CALCIPOTRIENE;Calciptriol, MC-903, Daivonex, Dovonex, Psorcutan;9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol, 24-cyclopropyl-, (1α,3β,5Z,7E,22E,24S)- |
CAS: | 112965-21-6 |
MF: | C27H40O3 |
MW: | 412.6 |
EINECS: | |
Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labelled Compounds |
Mol File: | 112965-21-6.mol |
Calcipotriene Chemical Properties |
Melting point | 166-168°C |
storage temp. | Desiccate at -20°C |
CAS DataBase Reference | 112965-21-6(CAS DataBase Reference) |
MSDS Information |
Provider | Language |
---|---|
Calcipotriene | English |
Calcipotriene Usage And Synthesis |
Chemical Properties | White Crystalline Solid |
Usage | An antipsoriatic. A vitamin D3 analogue with low calcemic activity |
Usage | antipsoriatic;viamin D receptor (VDR) affinity |
Usage | A labelled antipsoriatic. A vitamin D3 analogue with low calcemic activity. |
Biological Activity | Vitamin D 3 analog that displays minimal effects on calcium homeostasis. Regulates cell differentiation and proliferation; exhibits antiproliferative activity against human HL-60, HL60/MX2, MCF-7, T47D, SCC-25 and mouse WEHI-3 cancer cell lines. |
Calcipotriene Preparation Products And Raw materials |
Raw materials | Selenium dioxide -->tert-Butyldimethylsilyl chloride-->4-METHYLMORPHOLINE-4-OXIDE SOLUTION |