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Supply Rapamycin global trader Rapamycin Rapamycin exporter
Global trader supply Rapamycin 53123-88-9 exporter
Rapamycin (RAPA) has similar side effects as FK506. In a large number of clinical trials, it has been found that its side effects are dose-dependent and reversible. The therapeutic dose of RAPA has not been found to have obvious nephrotoxicity and no gingival hyperplasia. The main side effects include headache, nausea, dizziness, nose bleeding, joint pain. Laboratory abnormalities include: thrombocytopenia, leukopenia, hemoglobin reduction, hypertriglyceridemia, hypercholesterolemia, hyperglycemia, elevated liver enzymes (SGOT, SGPT), elevated lactate dehydrogenase, low potassium, Hypomagnesemia and so on. Recently, it has been reported that taking RAPA can cause eyelid swelling, and the reason for the lower plasma phosphate level is believed to be that RAPA-based immunosuppressive therapy prolongs the excretion of phosphate from the transplanted kidney. Like other immunosuppressants, RAPA has an increased chance of infection. It has been reported that it has a tendency to increase pneumonia, but the occurrence of other opportunistic infections is not significantly different from CsA.
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