High quality Imidocarb dipropionate Cas 55750-06-6 with specialized factory

Details:

Imidocarb dipropionate is a veterinary pharmaceutical compound primarily used as an antiprotozoal agent. Here's a structured overview:

Chemical Composition

Imidocarb: The active component, classified as an aromatic diamidine. The "imid" refers to an imidazoline group, and "carb" denotes its carbamide (urea) linkage.

Dipropionate: The salt form (two propionate ions) enhancing solubility and stability for injection.

Primary Use

Target Infections: Mainly treats babesiosis (caused by Babesia spp.) and anaplasmosis (caused by Anaplasma spp.) in animals, particularly livestock (cattle, sheep) and companion animals (dogs). These tick-borne diseases affect red blood cells, leading to anemia and systemic illness.

Mechanism of Action

Protozoal DNA Interaction: Binds to protozoal DNA, disrupting replication and transcription. Its diamidine structure may also interfere with mitochondrial function or cell membrane integrity.

Administration

Route: Typically administered via subcutaneous or intramuscular injection.

Dosage: Varies by species and infection severity. Overdose risks include toxicity (e.g., cholinergic effects like salivation, diarrhea, or organ damage).

Safety and Considerations

Withdrawal Periods: Critical in food-producing animals to prevent residue contamination.

Side Effects: Local reactions (pain/swelling at injection site), autonomic nervous system effects, or hepatotoxicity in high doses.

Resistance Management: Used judiciously to mitigate resistance development.

Regulatory Status

Veterinary Use Only: Not approved for human use due to toxicity profile, though rare off-label cases exist under strict medical supervision.

Conclusion

Imidocarb dipropionate is a vital tool in managing economically significant protozoal infections in animals, with its efficacy rooted in DNA-targeted action. Proper dosing and veterinary oversight are essential to ensure safety and effectiveness.