6-HYDROXYDOPAMINE H...

6-HYDROXYDOPAMINE HYDROCHLORIDE
6-HYDROXYDOPAMINE HYDROCHLORIDE
6-HYDROXYDOPAMINE HYDROCHLORIDE

6-HYDROXYDOPAMINE HYDROCHLORIDE

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1 Kilogram

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Keywords

6-HYDROXYDOPAMINE HYDROCHLORIDE 28094-15-7 C8H12ClNO3

Quick Details

  • Appearance:powder
  • Application:28094-15-7
  • PackAge:as requested
  • ProductionCapacity:300|Kilogram|Month
  • Storage:store in cool, dry place
  • Transportation:by sea or by air

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6-HYDROXYDOPAMINE HYDROCHLORIDE Basic information
Product Name: 6-HYDROXYDOPAMINE HYDROCHLORIDE
Synonyms: 6-OHDA;6-HYDROXYDOPAMINE HYDROCHLORIDE;2,4,5-TRIHYDROXYPHENETHYLAMINE HYDROCHLORIDE;2,5-DIHYDROXYTYRAMINE HYDROCHLORIDE;2-(2,4,5-TRIHYDROXYPHENYL)ETHYLAMINE HYDROCHLORIDE;TIMTEC-BB SBB003496;2,4-benzenetriol,5-(2-aminoethyl)-hydrochloride;5-(2-aminoethyl)-1,2,4-benzenetriolhydrochloride
CAS: 28094-15-7
MF: C8H12ClNO3
MW: 205.64
EINECS: 248-837-2
Product Categories:  
Mol File: 28094-15-7.mol
6-HYDROXYDOPAMINE HYDROCHLORIDE Structure
 
6-HYDROXYDOPAMINE HYDROCHLORIDE Chemical Properties
Melting point  232-233 °C (dec.)(lit.)
storage temp.  −20°C
solubility  H2O: >50 mg/mL, clear, yellow to brown
form  powder
color  off-white to brown
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  DC4650000
F  3-8-10-23
MSDS Information
Provider Language
SigmaAldrich English
 
6-HYDROXYDOPAMINE HYDROCHLORIDE Usage And Synthesis
Usage 6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells.
General Description Beige solid.
Air & Water Reactions Hygroscopic. Water soluble.
Reactivity Profile A weak acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.
Health Hazard ACUTE/CHRONIC HAZARDS: When heated to decomposition 6-HYDROXYDOPAMINE HYDROCHLORIDE emits very toxic fumes.
Fire Hazard Flash point data for 6-HYDROXYDOPAMINE HYDROCHLORIDE are not available. 6-HYDROXYDOPAMINE HYDROCHLORIDE is probably combustible.
Biological Activity Selective catecholaminergic neurotoxin. Depletes brain catecholamine levels via uptake and accumulation by a transport mechanism specific to these neurons. Causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats, producing an animal model of Parkinson's disease.
 
6-HYDROXYDOPAMINE HYDROCHLORIDE Preparation Products And Raw materials

 

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