Whitening OEM private label Nonapeptide Melanostatine Serum

Details:

Description

MELANOSTATINE™5 is a biomimetic peptide which inhibits the synthesis of melanin induced by α-MSH （Tip :Alpha Melanocyte Stimulating Hormone also named Melanotropin (a-MSH) is the natural substance produced by our body which is responsible for several physiological）and prevents its hyperproduction for a better control over skin tone and age spots. Melanostatine®5 does not interfere with the melanocyte’s functions thus it is an ideal skin lightening agent for cosmetic products that inhibits melanogenesis without cytotoxicity.

MELANOSTATINE™ 5 shows also clinical efficacy on Asian skin with a significant lightening effect after only 28 days.

Action :

Binding of a-MSH to the MC1-Receptor on melanocytes is the first step in melanogenesis and the pigment formation. By binding and blocking the MC1-R, we can block the intracellular melanogenesis pathway and decrease the synthesis or the over expression of melanin produced by melanocytes.

Melanostatine®5 is an oligopeptide with an high affinity for MC1-R. Melanostatine®5 is a biomimetic peptide antagonist specific of the a-MSH (Alpha Melanocyte Stimulating Hormone). As an antagonist, Melanostatine®5 competes against the natural ligand (a-MSH) on its specific receptor (MC1-R) by preventing any further activation of the tyrosinase, and thus blocking melanin synthesis. Tyrosinase inhibition reduces the formation of unwanted pigmentation allowing for the control over skin tone and brown spots.

Melanostatine®5 inhibits the synthesis of melanin induced by a-MSH by 33%

Properties ：

Proven effective on Asian skin

Prevents hyperproduction of melanin ， allowing a better control over skin tone.

Features and Benefits:

Features :

• Peptide Stable,
• a-MSH antagonist mechanism of action
• Clinical efficacy on Asian skin

Benefits :

• easy to work with 
• Reverses pigmentation without toxicity
• Significant lightening effect after only 28 days