CasNo.1405-20-5,High Quality CAS 1405-20-5 Polymyxin B Sulphate,(1405-20-5) Suppliers

10 Gram	FOB Price: USD 100.0000

Min.Order :10 Gram
Purity: 99.00%
Payment Terms : T/T,,MoneyGram,Other

Keywords

Polymyxin B Sulphate factory price Polymyxin B Sulphate real supplier 1405-20-5

Quick Details

Appearance:powder
Application:in research
PackAge:Aluminum foil bag/as requirements
ProductionCapacity:800|Kilogram|Month
Storage:store in a cool dry place and keep away from strong
Transportation:by air or by sea

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Details:

Product Description

1. Quick Detail:

CAS: 1405-20-5
Quality: EP/USP
Appearance: White to alomost white powder, hygroscopic

2. Description:

Polymyxin B sulfate/trimethoprim is an antibiotic eye drop composed of two drugs. Polymyxin B sulfate works by altering bacterial cell wall structure that causes the leaking out of cellular contents that can result in cell death. Trimethoprim is an antibiotic that interferes with the production of tetrahydrofolic acid, a chemical that is necessary for bacteria and human cells to produce proteins. Trimethoprim inhibits production of tetrahydrofolic acid by inhibiting the enzyme responsible for making tetrahydrofolic acid from dihydrofolic acid. This inhibition interferes with the ability of bacteria to survive. Polymyxin B sulfate/trimethoprim is effective against gram-positive and gram-negative bacteria such as Staphylococcus aureus and epidermis, Streptococcus pyogenes, Streptococcus faecalis, Streptococcus pneumonia, E. coli, Haemophilus influenzae, Klebsiella pneumoniae, and Pseudomonas aeruginosa. The FDA approved polymyxin B sulphate/trimethoprim in October 1988.

3. Specification:

ITEMS	SPECIFICATION of Polymyxin B Sulphate
DESCRIPTION	WHITE TO ALMOST WHITE POWDER,HYGROSCOPIC.
SOLUBILITY	FREELY SOLUBLE IN WATER;SLIGHTLY SOLUBLE IN ALCOHOL.
IDENTIFICATION	A. LIQUID CHROMATOGRAPHIC IDENTIFICATION TEST B. A REDDISH VIOLET COLOR IS PRODUCED C. TEST FOR SULFATE
PH(2%)	5.0~7.0
PH(0.5%)	5.0~7.5
SPECIFIC ROTATION	-78°- -90°
LOSS ON DRYING	NOT MORE THAN 7.0%
PHENYLALANINE	9.0%~12.0%
SULPHATED ASH	NOT MORE THAN 0.75%
SULPHATE	15.5%~17.5%
HEAVY METALS	NOT MORE THAN 20PPM
ASSAY(MICROBIAL) (ON DRIED BASIS)	NOT LESS THAN 6500IU/MG
PARTICLE SIZE	99.0%:NOT MORE THAN 30um BY VOL. 90.0%:NOT MORE THAN 25um BY VOL. 75.0%:NOT MORE THAN 20um BY VOL. MEAN DIAMETER:NOT MORE THAN 8.0UM

4. Applications:

This medication is used to treat bacterial infections (such as blepharitis, conjunctivitis) of the eye. It contains 2 antibiotics. Polymyxin B works by killing the bacteria.Trimethoprim works by stopping the growth of the bacteria.
This medication treats only bacterial eye infections. It will not work for other types ofeye infections. Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.