7-Ethyl-10-hydroxycamptothecin

Details:

CAS Number: 86639-52-3

Name: 7-Ethyl-10-hydroxycamptothecin

Formula: C₂₂H₂₀N₂O₅

Molecular Weight: 392.40

Synonyms: (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione;1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline- 3,14(4H,12H)-dione,4,11-diethyl-4,9- dihydroxy-,(4S)-;Captothecin, 7-ethyl-10-hydroxy-;1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4,7-diethyl-4,10-dihydroxy-;7-Ethyl-10-hydroxy-camptothecin;7-Ethyl-10-Hydroxycamptothecin (SN-38);7-Ethyl-10-Hydroxy CPT;7-Ethyl-10-Hydroxy Camptothecine;7-Ethyl-10-hydroxycamptothecin (TECANS);7-Ethyl-10-hydroxycamptothecin (SN38);7-Ethyl-10- Hydroxycamptothecin;7-Ehthy-10-Hydroxycamptothecin;7-etyl-10-hydroxycamptothecin;7-Ethyl-10-hydroxy-camptothecine;7-ethyl-Hydroxycamptothecin;7-ethyl-Camptothecin;

Density: 1.51 g/cm3

Melting Point: 217℃

Application: important intermediate for preparation of antineoplastic agents-irinotecan hydrochloride (CPT-11)( metabolite of Irinotecan), a DNA topoisomerase inhibitor

Boiling Point: 810.3℃ at 760 mmHg

Flash Point: 443.8℃

Appearance: light-yellow solid

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