Offer best price o...

Offer best price of Donepezil HCl 120011-70-3 global trader
Offer best price of Donepezil HCl 120011-70-3 global trader
Offer best price of Donepezil HCl 120011-70-3 global trader

Offer best price of Donepezil HCl 120011-70-3 global trader

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1 Kilogram

FOB Price: USD 1.0000

  • Min.Order :1 Kilogram
  • Purity: 99.0%
  • Payment Terms : T/T,Other

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Offer Donepezil HCl 120011-70-3 best price of Donepezil HCl Donepezil HCl global trader

Quick Details

  • Appearance:powder
  • Application:Pharmaceutical raw materials/intermediates
  • PackAge:fiber can/aluminum foil bag
  • ProductionCapacity:5.8|Kilogram|Month
  • Storage:20-25℃
  • Transportation:by air/by sea

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Donepezil

 
Systematic (IUPAC) name
(RS)-2-[(1-benzyl-4-piperidyl)methyl]- 5,6-dimethoxy-2,3-dihydroinden-1-one
Clinical data
Trade names Aricept
AHFS/Drugs.com monograph
MedlinePlus a697032
Pregnancy cat. C
Legal status  Prescription only
Routes Oral tablet, 5,10 & 23mg
Pharmacokinetic data
Bioavailability 100 (%)
Protein binding 96%
Half-life 70 hours
Excretion 0,11-0,13 (l/h/kg)
Identifiers
CAS number 120014-06-4 Yes
ATC code N06DA02
PubChem CID 3152
DrugBank DB00843
ChemSpider 3040 Yes
UNII 8SSC91326P Yes
KEGG D07869 Yes
ChEBI CHEBI:53289 Yes
ChEMBL CHEMBL502 Yes
Chemical data
Formula C24H29NO3 
Mol. mass 379.492 g/mol

Donepezil, marketed under the trade name Aricept by its developerEisai and partner Pfizer, and also marketed under the brand name DONEPby Alkem Pentacare, is a centrally acting reversibleacetylcholinesterase inhibitor.[1] Its main therapeutic use is in thepalliative treatment of Alzheimer's disease.[2] Common side effects include gastrointestinal upset. It has an oral bioavailability of 100% and easily crosses the blood–brain barrier. Because it has a biological half-life of about 70 hours, it can be taken once a day.

Details:

Offer  best price

of  Donepezil HCl

120011-70-3 global

trader

Donepezil

 
Systematic (IUPAC) name
(RS)-2-[(1-benzyl-4-piperidyl)methyl]- 5,6-dimethoxy-2,3-dihydroinden-1-one
Clinical data
Trade names Aricept
AHFS/Drugs.com monograph
MedlinePlus a697032
Pregnancy cat. C
Legal status  Prescription only
Routes Oral tablet, 5,10 & 23mg
Pharmacokinetic data
Bioavailability 100 (%)
Protein binding 96%
Half-life 70 hours
Excretion 0,11-0,13 (l/h/kg)
Identifiers
CAS number 120014-06-4 Yes
ATC code N06DA02
PubChem CID 3152
DrugBank DB00843
ChemSpider 3040 Yes
UNII 8SSC91326P Yes
KEGG D07869 Yes
ChEBI CHEBI:53289 Yes
ChEMBL CHEMBL502 Yes
Chemical data
Formula C24H29NO3 
Mol. mass 379.492 g/mol

Donepezil, marketed under the trade name Aricept by its developerEisai and partner Pfizer, and also marketed under the brand name DONEPby Alkem Pentacare, is a centrally acting reversibleacetylcholinesterase inhibitor.[1] Its main therapeutic use is in thepalliative treatment of Alzheimer's disease.[2] Common side effects include gastrointestinal upset. It has an oral bioavailability of 100% and easily crosses the blood–brain barrier. Because it has a biological half-life of about 70 hours, it can be taken once a day.

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