Tacrolimus raw mate...

Tacrolimus raw materials

Tacrolimus raw materials

Min.Order / FOB Price:Get Latest Price

1 Gram

FOB Price: USD 50.0000

  • Min.Order :1 Gram
  • Purity: 99
  • Payment Terms : T/T,,MoneyGram

Keywords

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Quick Details

  • Appearance:White powder
  • Application:Tacrolimus, also known as FK506, is a fermented product isolated from streptomyces tsukubaensis and its chemical structure is a 23-membered macrolide antibiotic. Is a powerful new immunosuppressive ag
  • PackAge:Foil bag
  • ProductionCapacity:50000|Kilogram|Week
  • Storage:Placed in a cool place
  • Transportation:

Superiority:

Tacrolimus, also known as FK506, is a fermented product isolated from streptomyces tsukubaensis and its chemical structure is a 23-membered macrolide antibiotic. Is a powerful new immunosuppressive agent, mainly by inhibiting the release of interleukin-2 (L-2), the total inhibition of T lymphocyte effect, than cyclosporine (CsA) 100 times stronger. In recent years, as a liver and kidney transplantation of first-line medication, has been in Japan, the United States and other 14 countries listed. Clinical experiments show that its heart, lung, intestine, bone marrow and other transplantation in the application of a good effect. At the same time FK506 in the treatment of atopic dermatitis (AD), systemic lupus erythematosus (SLE), autoimmune eye disease and other autoimmune diseases also play a positive role.

Details:

Tacrolimus
Synonyms: big ring piperazine
English name: Tacrolimus
CAS No.: 109581-93-3; 104987-11-3
Molecular formula: C44H69NO12
Molecular weight: 804.02
    Tacrolimus, also known as FK506, is a fermented product isolated from streptomyces tsukubaensis and its chemical structure is a 23-membered macrolide antibiotic. Is a powerful new immunosuppressive agent, mainly by inhibiting the release of interleukin-2 (L-2), the total inhibition of T lymphocyte effect, than cyclosporine (CsA) 100 times stronger. In recent years, as a liver and kidney transplantation of first-line medication, has been in Japan, the United States and other 14 countries listed. Clinical experiments show that its heart, lung, intestine, bone marrow and other transplantation in the application of a good effect. At the same time FK506 in the treatment of atopic dermatitis (AD), systemic lupus erythematosus (SLE), autoimmune eye disease and other autoimmune diseases also play a positive role.
Indications: liver. Heart. Bone marrow and bone marrow transplant patients preferred immunosuppressive drugs, rejection after transplantation on traditional immunosuppressive regimens, can also use the drug. Adverse reactions are similar to cyclosporine.
Appearance: white crystalline powder, soluble in methanol, ethyl acetate, chloroform.
Melting point: 125-129 ° C
Moisture: ≤3.0%
Specific rotation [α] 23 ° C, chloroform: -75--90 °
Heavy metals: <10PPM
Residue on ignition: ≤0.1%
Total impurities: ≤2%
Content: ≥98%
 KG pharmaceutical grade crystal white 2g / aluminum foil bag

 

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