AZD9291 Osimertinib AZD-9291 1421373-65-0
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Product Name: AZD9291
Other Names: Osimertinib; mereletinib
CAS No: 1421373-65-0
Molecular Formula: C28H33N7O2
Molecular Weight: 499.607
Purity: 99%
Appearance: white powder
Osimertinib (previously known as mereletinib or AZD9291; trade name Tagrisso) is a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals – for mutated EGFR cancers.
Product Name: AZD9291
Other Names: Osimertinib; mereletinib
CAS No: 1421373-65-0
Molecular Formula: C28H33N7O2
Molecular Weight: 499.607
Purity: 99%
Appearance: white powder
Osimertinib (previously known as mereletinib or AZD9291; trade name Tagrisso) is a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals – for mutated EGFR cancers.
Product Name: AZD-9291 | Batch No.: BOZ/AZD/17/Jan/06 |
CAS No.: 1421373-65-0 | Quantity: 4KG |
Manufacturing Date: Jan., 6th, 2017 | Text Date: Jan., 7th, 2017 |
Expiry Date: Jan., 5th, 2019 | Quality Standard: Enterprise Standard |
TEST | SPECIFICATION | RESULT |
Physical Characters | ||
Appearance | White powder | Conforms |
Identification | The retention time of text sample major peak conforms to reference standard. | Conforms |
Impurities | ||
single impurity |
≤0.2% |
0.18% |
Chemical Characters | ||
Heavy Metals | ≤20PPM | Conforms |
Residue on Ignition |
≤0.2% |
0.05% |
Loss on Drying | ≤0.5% | 0.13% |
Solvent residue |
Dioxane≤380ppm Acetone≤5000ppm Acetonitrile≤410ppm |
Not detected 482ppm 22ppm |
Assay (by HPLC) | 98.5% min. | 99.81% |
Packing - Fluoride bottle or as required. Storage - Store in well closed container away from oxides and acids. |
Conclusion: The above analysis results comply with the specification. Customer is advised to verify the results before use.
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