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Lidocaine hydrochloride 73-78-9 Lidocaine hcl
Lidocaine Hydrochloride,Local Anesthetic Drugs Lidocaine, also known as xylocaine and lignocaine , is a medication used to numb tissue in a specific area and to treat ventricular tachycardia . It can also be used for nerve blocks . Lidocaine mixed with a small amount of epinephrine is available to allow larger doses to be used as numbing and to make it last longer . When used as an injectable it typically begins working within four minutes and lasts for half an hour to three hours . Lidocaine may also be applied directly to the skin for numbing.
Lidocaine Hydrochloride,Common side effects with intravenous use include sleepiness, muscle twitching , confusion , changes in vision , numbness , tingling, and vomiting . It can cause low blood pressure and an irregular heart rate.There are concerns that injecting it into a joint can cause problems with the cartilage . It appears to be generally safe for use in pregnancy . A lower dose may be required in those with liver problems . It is generally safe to use in those allergic to tetracaine or benzocaine . Lidocaine is an antiarrhythmic medication of the class Ib type . Lidocaine works by blocking sodium channels and thus decreasing the rate of contractions of the heart . When used locally as a numbing agent, local neurons cannot signal the brain.
Lidocaine Hydrochloride,Local Anesthetic Drugs Lidocain was discovered in 1946 and went on sale in 1948 . It is on the WHO Model List of Essential Medicines , the most important medications needed in a basic healthcare system . It is available as a generic medication and is not very expensive . The wholesale cost in the developing world in 2014 was US$0.45 to $1.05 wholesale per 20ml vial of medication .
Specification
ITEMS |
SPECIFICATION |
RUSULTS |
Appearance of solution |
Clear and colourless powder |
Complies |
Characters |
A white, crystalline powder, very soluble in water, freely soluble in alcohol. |
Complies |
Identification |
IR |
Complies |
PH |
4.0-5.5 |
Complies |
Sulphated ash |
MAX. 0.1% |
Complies |
Heavy Metals |
MAX. 10 ppm |
Complies |
Lead |
MAX. 3ppm |
Complies |
Cadmium |
MAX. 1ppm |
Complies |
Mercury |
MAX. 0.1ppm |
Complies |
Loss on drying |
Max. 1.0% |
0.47% |
Specific Rotation |
+98°~ +108° |
+103° |
Impurity (2,6-dimethylaniline) |
Meets the requirements |
Complies |
Mesh Size |
100% pass80 mesh |
Complies |
Assay by HPLC on anhydrous substance |
99%~101% |
99.67% |
Total Aerobes Count Yeast & Mold E.Coli. Salmonella |
Max.1000cfu/g Max.100cfu/g Negative Negative |
≤100 cfu/g ≤10 cfu/g Negative Negative |
Lidocaine Hydrochloride,The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy . Therefore, lidocaine is suitable for infiltration , block , and surface anesthesia . Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias ; lidocaine , though , has the advantage of a rapid onset of action .
Lidocaine Hydrochloride,Epinephrine (adrenaline) vasoconstricts arteries , reducing bleeding and also delays the resorption of lidocaine , almost doubling the duration of anaesthesia . For surface anesthesia, several available formulations can be used for endoscopies , before intubations , etc . Buffering the pH of lidocaine makes local numbing less painful . Lidocaine drops can be used on the eyes for short ophthalmic procedures . There is tentative evidence for topical lidocaine for neuropathic pain.
Packaging and Delivery
Package: 25kg/drum or as your request.
Storage Situation: Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Shelf Life: Two years when properly stored.
Delivery: within two weeks after receiving your prepayment.
Company information
Kono Chem., Ltd was established in 2014, which is subordinated to PIONEER BIOTECH HongKong, and has got great support from the State Department of Commerce as one of the most promising
export-oriented manufacturing enterprises.
Kono Chem is head-quarted in Xi’ an Shaanxi Province, China, with convenient transportation
access, covering an area of 312, 000 square meters, and technicians accounted for 35% of the total employees. Presently, we have two chemical fermentation plant, one test reaction plant, and one
Provincial Research and Development Center now. Our well-equipped facilities and excellent
quality control throughout production enables us to guarantee customer satisfaction.
From the very beginning, we strictly manage our production according to the demand of ISO9000,ISO14001, now has received the recognition from customers all over the world and has passed the audit by authoritative labs. At present, our products are mainly related to bio-pharmaceuticals, flavors,
intermediates of pesticides, veterinary drugs development, as well as some custom synthesis.
Thanks to our EHS management system and high quality control, now 85% of our products are
well-selling and appreciated in almost 50 countries all over the world, and established long-term cooperative business relationship with multinational companies such as CIPLA,BIOCON,DSM.
Persisting to the principle of “Integrity and diligence”, we are rising up with hardworking employees and efficient research and development system. We are engaging to play an active role in the development of chemical industry together with you!
yoyo
Tel: +86 29 84385017-8006
Mobile: 18049631948
QQ: 3011124028
Email: sales3@konochemical.com
Web: www.konochemical.com
Address:11 Daqing Road, Xi’an, Shaanxi 710082, P.R China
Kono Chem Co., Ltd
FAQ
1.Q:Are you a factory or trading company
A: We are a trading company, we are professional supplier and specialize in plastic bottle for pharmaceutical,cosmetic and food packing.
2.Q:What is the general payment terms
A: L/C, T/T, D/A, Western Union , Paypal .
3.Q:Can you make sample
A: Yes, we can make sample for you.
4.Q: What is minimum order for plastic bottle
A: Our Plastic bottle China is 1KG.
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