CasNo.29342-05-0,High quality Ciclopirox Ciclopirox Supplier Ciclopirox Manufacturer,(29342-05-0) Suppliers

10 Kilogram	FOB Price: USD 1.0000

Min.Order :10 Kilogram
Purity: 99%
Payment Terms : T/T,

Keywords

Ciclopirox High quality Ciclopirox CAS No.:29342-05-0

Quick Details

Appearance: colorless or light yellow transparent liquid
Application:oom temperature vulcanized silicone rubber and silicone glass sealant cross-linking agent
PackAge:inner plastic and outer iron drum; net weigth is 25kg, 200kg
ProductionCapacity:50|Metric Ton|Day
Storage: in seal container under cool, dry and lucifugal place
Transportation:EMS、TNT、DHL、UPS、FEDEX、SF、Wuhan Port、Shanghai Port、Tianjin Port、Guangzhou Port

Superiority:

1.High quality and competetive price
1)For Prulifloxacin exported we can offer COA Certificate and official Invoice.
2)We are manufacturer with own lab and factory, can provide high quality products with factory price.
3)Products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (SGS/ CTI/ ITS), only after your confirmation will we send it out to you.

2.Fast and safe delivery:
1)Products can be sent out one or four weeks after payment. Tracking number available, fixed service person are 7x24h for you to contact.
2) Secure and discreet shipment. Various transportation methods for your choice, like DHL/UPS/TNT/FedEx/SF-express.
3)Customs pass and satisfied rate ¡Ý99%.
4)For hot sale products we have stock in there for transferring.

3 We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

Details:

Product Name: Ciclopirox

Synonyms: 6-CYCLOHEXYL-1-HYDROXY-4-METHYL-1H-PYRIDIN-2-ONE;CICLOPIROX;CIELOPIROX;6-Cyclohexyl-1-hydroxy-4-methyl-2[1H]-pyridinone;6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone;Brumixol;Ciciopirox;Cidochem

CAS: 29342-05-0

MF: C12H17NO2

MW: 207.27

EINECS: 249-577-2

Topical antifungal Ciclopirox is a novel broad-spectrum topical antifungal agent,it is successfully developed by pharmaceutical companies of the Federal Republic of Germany , the mechanism is by changing the integrity of the fungal cell membrane, causing intracellular material outflow, and blocking intake of protein precursors, resulting in fungal cell death, it has a strong bactericidal effect against dermatophytes, yeasts, molds, etc. And it has strong permeability . At higher concentrations,it can also have a certain extent inhibiting effect on a variety of actinomycetes, Gram-positive and Gram-negative bacteria and mycoplasma, chlamydia, trichomonas, Trichomonas vaginalis and Pseudomonas aeruginosa.

Compared with imidazole antifungal, ciclopirox has strong penetration ability in cuticle where skin fungus survive, so it has a significant inhibition effect on the cuticle deep fungi, such as onychomycosis.

Mainly it is used in clinical for superficial skin fungal infections, such as ringworm, athlete's foot, jock itch, tinea manus and pedis(especially keratosis thickening), tinea versicolor, skin candidiasis, Candida albicans and onychomycosis treatment.

The above information is edited by the chemicalbook of Tian Ye.

Chemical Properties Solid, m.p. 144 ℃.

Ciclopirox Olamine: [41621-49-2]. White crystalline powder, odorless, bitter taste. Soluble in methanol, ethanol or chloroform, slightly soluble in dimethylformamide or water, slightly soluble in ether. Melting point 124-128 ℃. Acute toxicity LD50 in mice, rats (mg/kg): 2898,3290 orally.

Uses Pyridine ketones broad-spectrum antifungal agents, have inhibiting effects on a variety of skin fungi . They can prevent the substances necessary for Candida albicans cells survival such as amino acids, potassium ions, phosphate,going through the cell membrane ,which can cause by certain important matrix or intracellular ions failure,and then inhibit or kill fungal cells. There are a wide range of anti-fungal effects, they can have a killing effect on the skin filamentous bacteria, yeast fungi , they have inhibition effects on a variety of Gram positive and negative bacteria, chlamydia, trichomoniasis, Proteus, E. coli, Pseudomonas and Staphylococcus bacteria. They are used to treat fungal skin disease, tinea versicolor, vulvovaginal Candida disease, skin and fingers (toe) candidiasis ,they have significant effects , and lower side effects.