H-89 dihydrochloride

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100 Metric Ton	Negotiable

100 Metric Ton

Negotiable

Min.Order :100 Metric Ton
Purity: 98%
Payment Terms : L/C,T/T,Other

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127243-85-0 H-89 dihydrochloride seller in China Sell high quality 127243-85-0 produced in China factory

Quick Details

Appearance:White solid
Application:Pharmaceutical Intermedaite
PackAge:1g, 10g, 100g, 1kg
ProductionCapacity:100|Metric Ton|Day
Storage:Store in a cool,dry place and keep away from direct strong light
Transportation:Common products:Sea/Air/Courier Dangerous Chem:Sea/Air

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Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin has demonstrated efficacy in obese and overweight populations by promoting weight loss and improving metabolic parameters, and it is well tolerated.

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Product Name:	H-89 dihydrochloride
Synonyms:	H-89;H-89 DIHYDROCHLORIDE;H-89 HYDROCHLORIDE;N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE;N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE 2HCL;N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, DIHYDROCHLORIDE;N-(2-[P-BROMOCINNAMYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE;N-[2-[P-BROMOCINNAMYLAMINO]-ETHYL]-5-ISOQUINOLINESULFONMIDE
CAS:	127243-85-0
MF:	C20H20BrN3O2S
MW:	446.36
EINECS:
Product Categories:	Protein Kinase Inhibitors and Activators;Inhibitor
Mol File:	127243-85-0.mol

H-89 dihydrochloride Chemical Properties

mp	195-200°C
density	1.436
storage temp.	2-8°C
solubility	H₂O: ≥10 mg/mL
form	powder
color	off-white
CAS DataBase Reference	127243-85-0(CAS DataBase Reference)

Safety Information

Safety Statements	22-24/25
WGK Germany	3

MSDS Information

H-89 dihydrochloride Usage And Synthesis

Chemical Properties	White Solid
Usage	Selective inhibitor of Protein Kinase A (cyclic AMP-dependeant Protein Kinase) with an inhibitory constant of 0.0048 uM
Biological Activity	Protein kinase A inhibitor that also inhibits several other kinases (IC 50 values are 80, 120, 135, 270, 2600 and 2800 nM for S6K1, MSK1, PKA, ROCKII, PKB α and MAPKAP-K1b).

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H-89 dihydrochloride