Sorafenib

Sorafenib
Sorafenib
Sorafenib
Sorafenib

Sorafenib

Min.Order / FOB Price:Get Latest Price

100 Gram

FOB Price: USD 7.0000

  • Min.Order :100 Gram
  • Purity: 98% min
  • Payment Terms : L/C,T/T,Other

Keywords

284461-73-0 Sorafenib 98% Sorafenib

Quick Details

  • Appearance:C21H16ClF3N4O3
  • Application:Used for research and industrial manufacture.
  • PackAge:As customer request
  • ProductionCapacity:100|Kilogram|Month
  • Storage:3 years -20°C powder; 2 years -80°C in solvent;
  • Transportation:Common products:Sea/Air/Courier Dangerous Chem:Sea/Air

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Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin has demonstrated efficacy in obese and overweight populations by promoting weight loss and improving metabolic parameters, and it is well tolerated.

Details:

 

Molecular Weight 464.83
Formula C21H16ClF3N4O3
CAS Number 284461-73-0
Solubility DMSO: 63 mg/mL warmed (135.53 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.

 

 

 

 

 

 

 

 

 

Sorafenib (rINN), marketed as Nexavar by Bayer, is a drug approved for the treatment of advanced renal cell carcinoma (primary kidney cancer). It has also received "Fast Track" designation by the FDA for the treatment of advanced hepatocellular carcinoma (primary liver cancer), and has since performed well in Phase III trials. Sorafenib is a small molecular inhibitor of Raf kinase, PDGF (platelet-derived growth factor), VEGF receptor 2 & 3 kinases and c Kit the receptor for Stem cell factor. A growing number of drugs target most of these pathways. The originality of Sorafenib lays in its simultaneous targeting of the Raf/Mek/Erk pathway.

 

 

 

 

 

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