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Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin has demonstrated efficacy in obese and overweight populations by promoting weight loss and improving metabolic parameters, and it is well tolerated.
Test Items
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Specification
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Test Results
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|
Description
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White or off-white crystalline powder
|
Off-white crystalline powder
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|
Specific rotation
|
-56°~-60°
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-58.2°
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Identification
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IR
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Matches with working standard
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Complies
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HPLC
|
|||
Solubility
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Freely soluble in chloroform and in alcohol; Very slightly soluble in water
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Conform
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Heavy metals
|
≤10ppm
|
<10ppm
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Water
|
≤0.3%
|
0.22%
|
|
Residue on ignition
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≤0.1%
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0.05%
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Relative material
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Maximum impurities≤0.5%
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0.36%
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|
Total impurities≤1.0%
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0.52%
|
||
Assay
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98.5~101.0%
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99.68%
|
|
Conclusion
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The specification conform with Enterprise standard
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