19171-19-8 Pomalidomide seller in China Pomalidomide factory in China
PRODUCT INFORAMTOIN :
4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione Basic information |
Product Name: |
4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione |
Synonyms: |
3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide;4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione;Pomalidomide;Pomalidomide(CC-4047);ActiMid;CC-4047;4-AMino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;1H-Isoindole-1,3(2H)-dione,4-aMino-2-(2,6-dioxo-3-piperidinyl)- |
CAS: |
19171-19-8 |
MF: |
C13H11N3O4 |
MW: |
273.24 |
EINECS: |
|
Product Categories: |
Inhibitor;CC-4047;Inhibitors |
Mol File: |
19171-19-8.mol |
|
4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione Chemical Properties |
storage temp. |
2-8°C |
Safety Information |
MSDS Information |
4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione Usage And Synthesis |
Chemical Properties |
Yellow Solid |
Usage |
Pomalidomide is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma. |
Usage |
Pomalidomide is a second generation immunomodulator, TNF-α inhibitor, and thalidomide analog. An inhibitor of LPS-induced TNFαrelease. |
Usage |
Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM |
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