cabozantinib (S)-malate

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100 Metric Ton	Negotiable

100 Metric Ton

Negotiable

Min.Order :100 Metric Ton
Purity: 98%min
Payment Terms : L/C,T/T,,MoneyGram,Other

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1140909-48-3 Sell high quality cabozantinib (S)-malate produced in China factory 1140909-48-3 seller in China

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Appearance:white powder
Application:Used for research and industrial manufacture.
PackAge:As customer request
ProductionCapacity:100kg/Month |Metric Ton|Day
Storage:Store in a cool,dry place and keep away from direct strong light
Transportation:Common products:Sea/Air/Courier Dangerous Chem:Sea/Air

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Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin has demonstrated efficacy in obese and overweight populations by promoting weight loss and improving metabolic parameters, and it is well tolerated.

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ProName: Cabozantinib Malate
CasNo: 1140909-48-3
Molecular Formula: C32H30FN3O10
Appearance: powder
Application: 1140909-48-3
DeliveryTime: within 3-7 days
PackAge: as requested
Port: China Main Port
ProductionCapacity: 300 Kilogram/Month
Purity: 98%
Storage: store in cool, dry place
Transportation: by sea or by air
LimitNum: 1 Kilogram

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Cabozantinib Malate Basic information

Product Name:	Cabozantinib Malate
Synonyms:	(2S)-2-Hydroxybutanedioic acid compd. with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1);Cabozantinib (S)-malate;Cabozantinib L-Malate Salt;N-[4-[(6,7-DiMethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxaMide (2S)-;Cabozantinib (S)-Malate(XL-184);Cabozantinib L-Malate;Cabozantinib Malate (XL184);XL-184 (Malate)
CAS:	<a keyword="1140909-48-3" "="" style="margin: 0px auto; padding: 0px; border: 0px; color: rgb(0, 51, 153); outline: none;">1140909-48-3
MF:	C32H30FN3O10
MW:	635.5931032
EINECS:
Product Categories:	Inhibitors
Mol File:	1140909-48-3.mol

Cabozantinib Malate Chemical Properties

Safety Information

MSDS Information

Cabozantinib Malate Usage And Synthesis

Chemical Properties	Off-White Solid
Usage	Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell a poptosis.
Usage	XL184 (Cabozantinib, BMS-907351) is a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively.
Usage	Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respective

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