fenbendazole

fenbendazole
fenbendazole

fenbendazole

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100 Gram

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  • Min.Order :100 Gram
  • Purity: 98% min
  • Payment Terms : L/C,T/T,,MoneyGram,Other

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43210-67-9factory in China fenbendazole factory in China 43210-67-9 seller in China

Quick Details

  • Appearance:Off-White Solid
  • Application:Used for research and industrial manufacture.
  • PackAge:As customer request
  • ProductionCapacity:100|Kilogram|Month
  • Storage:Store in a cool,dry place and keep away from direct strong light
  • Transportation:Common products:Sea/Air/Courier Dangerous Chem:Sea/Air

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Fenbendazole Basic information
Benzimidazole anthelmintics Aofendazuo Chemical Properties Uses Production method
Product Name: Fenbendazole
Synonyms: [5-(PHENYLTHIO)-1H-BENZIMIDAZOL-2-YL]CARBAMIC ACID, METHYL ESTER;HOE-881V;FENBENDAZOLE;METHYL 5-(PHENYLTHIO)-2-BENZIMIDAZOLECARBAMATE;SAFEGARD;PANACUR;(5-(phenylthio)-1h-benzimidazol-2-yl)-carbamicacimethylester;5-(phenylthio)-2-benzimidazolecarbamicacimethylester
CAS: 43210-67-9
MF: C15H13N3O2S
MW: 299.35
EINECS: 256-145-7
Product Categories: PHARMACEUTICALS;Active Pharmaceutical Ingredients;API;Intermediates & Fine Chemicals;Veterinaries;Amines;Aromatics;Heterocycles;Sulfur & Selenium Compounds;ProteasomeInhibitors;PANACUR;Other APIs;vermifuge
Mol File: 43210-67-9.mol
Fenbendazole Structure
 
Fenbendazole Chemical Properties
Melting point  233°C
storage temp.  0-6°C
CAS DataBase Reference 43210-67-9(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  DD6520500
MSDS Information
 
Fenbendazole Usage And Synthesis
Benzimidazole anthelmintics Fenbendazole is a benzimidazole anthelmintic with a broad spectrum,high efficiency and low toxicity ,in the structure,it has a strong affinity with the parasite tubulin ,by influencing cell transport and energy metabolism,it plays a role in preventing the polymerization of micro tubes, which ultimately destroys the integrity of parasite cells and energy transmission. 
Fenbendazole is used to drive and to kill the animal gastrointestinal parasites, it not only has a highly anthelmintic activity on animal gastrointestinal roundworms, hookworms, whipworms, some tapeworms and nematodes , but also has a preferred effect on the part of the bronchial tree and lung parasites (Aelurostrongylus abstrutus and lung fluke) .
Aofendazuo Aofendazuo is a benzimidazole anthelmintic, also known as the Austrian phenol metronidazole, oxfendazole, benzene etomidate sulfoxide, benzene sulfur oxygen imidazole ,it is the sulfoxide form of Fenbendazole , white or off-white powder at room temperature, slight special smell, it can damage the microtubules of the worms epithelial cells of the gastrointestinal tract, and inhibit the worms uptake of glucose from the intestine. 
Aofendazuo is used for the treatment and control of gastrointestinal adults and larvae, it has a good effect on the treatment of in vivo roundworms and lung worms in pigs and sheep , including Oster nematodes (Ostertagia), Haemonchus , Trichostrongylus, Nematodirus , Cooper nematode (Cooperia), capillary nematodes (Capillaria), toothed Oesophagostomum (Oesophagostomum), Chabertia, Trichuris nematodes form (Trichuris) and dictyocaulasis ( Dictyocaulus) and so on. 
The above information is edited by the chemicalbook of Tian Ye.
Chemical Properties Gray light brown crystalline powder. Melting point 233 ℃ (decomposition). Soluble in dimethyl sulfoxide (DMSO), slightly soluble in common organic solvents, insoluble in water. Odorless, tasteless.
Uses Anthelmintic. Broad-spectrum, high efficiency, low toxicity, antiparasitic. It has a strong killing effect on Roundworm, nematodes, tapeworms, cysticercosis , Fasciola and other parasites, not only killing worms, especially having a great effect on Transitional larvae ehich are hazardous to the liver, lungs and intestines .Fenbendazole is a benzimidazole anthelmintic, not only having a highly anthelmintic activity for gastrointestinal nematodes adults and larvae , but also having a good effect on dictyocaulasis, flukes and tapeworms, in addition,it has a strong killing eggs effect.
Production method 5-chloro-2-nitroaniline reacts with benzene thiol, to thereby obtain 5-phenylthio-2-nitroaniline in 91% yield.Generate 3-phenylthio-o-phenylenediamine by ferrous sulfate-iron reduction in 90% yield. Finally, cyclize it with the S-methyl-melamine Methyl to obtain fenbendazole.
Chemical Properties Off-White Solid
Uses An anthelmintic (Nematodes)
Definition ChEBI: A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in v terinary medicine, for the treatment of nematodal infections.
 
Fenbendazole Preparation Products And Raw materials
Preparation Products Oxfendazole
Raw materials Chloroform-->Acetonitrile-->Iron-->o-Phenylenediamine-->3-Chloroaniline-->Thiophenol-->5-Chloro-2-nitroaniline-->5-PHENYLTHIO-2-NITROANILINE

 

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