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Primidone Basic information |
Product Name: | Primidone |
Synonyms: | 2-deoxyphenobarbital;2-DESOXYPHENOBARBITAL;5-ETHYLDIHYDRO-5-PHENYL-4,6(1H,5H)-PYRIMIDINEDIONE;5-phenyl-5-ethyl-hexahydropyrimidine-4,6-dione;PRIMIDONE;4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-phenyl-;5-Aethyl-5-phenyl-hexahydropyrimidin-4,6-dion;5-Ethyl-5-phenyldihydro-4,6(1H,5H)-pyrimidinedione |
CAS: | 125-33-7 |
MF: | C12H14N2O2 |
MW: | 218.25 |
EINECS: | 204-737-0 |
Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;GABA/Glycine receptor;MYSOLINE |
Mol File: | 125-33-7.mol |
Primidone Chemical Properties |
Melting point | 281-282°C |
storage temp. | Store at RT |
Water Solubility | <0.1 g/100 mL at 19 ºC |
CAS DataBase Reference | 125-33-7(CAS DataBase Reference) |
NIST Chemistry Reference | Primidone(125-33-7) |
EPA Substance Registry System | 4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-phenyl-(125-33-7) |
Safety Information |
Hazard Codes | Xn,T,F |
Risk Statements | 22-40-39/23/24/25-23/24/25-11 |
Safety Statements | 22-36-45-36/37-16-7 |
RIDADR | 3249 |
WGK Germany | 3 |
RTECS | UV9100000 |
HazardClass | 6.1(b) |
PackingGroup | III |
Hazardous Substances Data | 125-33-7(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
Primidone | English |
SigmaAldrich | English |
Primidone Usage And Synthesis |
Chemical Properties | Crystalline Solid |
Uses | Anticonvulsant |
Definition | ChEBI: A pyrimidone that is dihydropyrimidine-4,6(1H,5H)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an anticonvulsant for treatment of various types of seizures. |
General Description | Odorless white crystalline powder. Slightly bitter taste. No acidic properties. |
Air & Water Reactions | Insoluble in water. |
Reactivity Profile | Primidone is an amide. May react with azo and diazo compounds to generate toxic gases. May react with strong reducing agents to form flammable gases. A very weak base. The Combustion generates toxic mixed oxides of nitrogen (NOx). |
Fire Hazard | Flash point data for Primidone are not available; however, Primidone is probably combustible. |
Biological Activity | Anticonvulsant. |
Primidone Preparation Products And Raw materials |
Raw materials | Diethyl 2-ethyl-2-phenylmalonate |
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