Posaconazole Posaconazole 171228-49-2
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Posaconazole Basic information
Product Name: | Posaconazole |
Synonyms: | Posaconazole;2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol;Noxafil;Sch 56592;4-[4-[4-[4-[[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one;HYDROXYPROPYL]-2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONE;Posaconazole for research;1-((1S,2S)-1-Ethyl-2-hydroxypropyl)-4-{4-[4-(4-{[(5S,3R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazolylmethyl)oxolan-3-yl]methoxy}phenyl)piperazinyl]phenyl}-1,2,4-triazolin-5-one |
CAS: | 171228-49-2 |
MF: | C37H42F2N8O4 |
MW: | 700.78 |
EINECS: | 200-659-6 |
Product Categories: | Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;API;Noxafil;Inhibitors |
Mol File: | 171228-49-2.mol |
Posaconazole Chemical Properties |
mp | 170-1720C |
storage temp. | -20°C Freezer |
CAS DataBase Reference | 171228-49-2(CAS DataBase Reference) |
Safety Information |
Hazard Codes | F,T |
Risk Statements | 11-23/24/25-39/23/24/25 |
Safety Statements | 7-16-36/37-45 |
Hazardous Substances Data | 171228-49-2(Hazardous Substances Data) |
Posaconazole Usage And Synthesis |
Chemical Properties | White Solid |
Usage | Orally active triazole antifungal. |
Usage | Posaconazole is a sterol C14ɑ demethylase inhibitor with an IC50 of 0.25 nM |
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