59-30-3 Folic acid PTEROYL-L-GLUTAMIC ACID
Synonyms: PTEROYL-L-GLUTAMIC ACID;PTEROYLMONOGLUTAMIC ACID;PTEROYLGLUTAMIC ACID;PTEROYGLUTAMIC ACID;PTEGLU;PGA;N-[4-[[(2-AMINO-4-HYDROXY-6-PTERIDYL)METHYL]AMINO]BENZOYL]GLUTAMIC ACID;n-4-[(2-amido-4-oxo-1,4-dihydro-6-terene)methylamino]benzoyl-l-glutamic acid
CAS: 59-30-3
MF: C19H19N7O6
MW: 441.4
EINECS: 200-419-0
Product Categories: Food and Feed Additive;Biochemistry;Vitamins;Nutritional Supplements;Vitamin Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;FOLICET;vitamin;food or feed additives;Inhibitors
Mol File: 59-30-3.mol
Folic acid Structure
Folic acid Chemical Properties
Melting point 250 °C
alpha 20 º (c=1, 0.1N NaOH)
storage temp. 2-8°C
Water Solubility 1.6 mg/L (25 ºC)
Merck 4221
Stability: Stable. Incompatible with heavy metal ions, strong oxidizing agents, strong reducing agents. Solutions may be light and heat sensitive.
CAS DataBase Reference 59-30-3(CAS DataBase Reference)
NIST Chemistry Reference Folic acid(59-30-3)
EPA Substance Registry System L-Glutamic acid, N-[4-[[(2-amino-1,4-dihydro- 4-oxo-6-pteridinyl)methyl] amino]benzoyl]-(59-30-3)
Safety Information
Risk Statements 33-62-68
Safety Statements 24/25
WGK Germany 1
RTECS LP5425000
F 8
TSCA Yes
Hazardous Substances Data 59-30-3(Hazardous Substances Data)
Chemical Properties orange to yellow crystalline powder
Uses A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.
Uses hematopoietic vitamin
Definition ChEBI: An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation.
General Description Odorless orange-yellow needles or platelets. Darkens and chars from approximately 482°F.
Air & Water Reactions Insoluble in water. Aqueous solutions have pHs of 4.0-4.8.
Reactivity Profile Acid solutions of Folic acid are sensitive to heat, but towards neutrality, stability progressively increases. Solutions are inactivated by ultraviolet light and alkaline solutions are sensitive to oxidation. Folic acid is also inactivated by light. Folic acid is incompatible with oxidizing agents, reducing agents and heavy metal ions.
Fire Hazard Flash point data for Folic acid are not available; however, Folic acid is probably combustible.
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