2-Amino-6-methylpyridine

Details:

1. Introduction of 2-Amino-6-methylpyridine

2-Amino-6-methylpyridine (CAS NO.1824-81-3) is a chemical whose appearance is similar white to slight yellow crystal or liquid. We can provide 98%min(GC) of 2-Amino-6-methylpyridine. The packaging of this chemical can be in the plastic drum. The FOB of this product is 0-100000 USD/kilogram. You can use it as a intermediates. We will delivery it form the beijing port. Our production capacity is 10 metric ton per year.

Other detailed specification:

Appearance :Similar white to slight yellow crystal or liquid
Assay :≥98.0%(GC)
Melting Point: 41-45℃(≤2℃)
Moisture :≤0.5%
Synonyms:  2-Amino-6-picoline
Formula: C₆H₈N₂
M.W.: 108.14 
Feature:     Similar white to slight yellow crystal or liquid , mp 41-45℃.B.p.208-209℃.fp103℃.

2. Basic information of 2-Amino-6-methylpyridine

1) Properties:

(1)XLogP3: 0.4; (2)H-Bond Donor: 1; (3)H-Bond Acceptor: 2; (4)Rotatable Bond Count: 0; (5)Tautomer Count: 5; (6)Exact Mass: 108.068748; (7)MonoIsotopic Mass: 108.068748; (8)Topological Polar Surface Area: 38.9; (9)Heavy Atom Count: 8; (10)Formal Charge: 0; (11)Complexity: 72.9; (12)Isotope Atom Count: 0; (13)Defined Atom Stereocenter Count: 0; (14)Undefined Atom Stereocenter Count: 0; (15)Defined Bond Stereocenter Count: 0; (16)Undefined Bond Stereocenter Count: 0; (17)Covalently-Bonded Unit Count: 1; (18)Feature 3D Acceptor Count: 1; (19)Feature 3D Donor Count: 1; (20)Feature 3D Cation Count: 1; (21)Feature 3D Ring Count: 1; (22)Effective Rotor Count: 0; (23)Conformer Sampling RMSD: 0.4; (24)CID Conformer Count: 1.

2) Physical Property

Physical Property	Value	Units	Temp (deg C)	Source
Melting Point	41	deg C		EXP
Boiling Point	208.5	deg C		EXP
log P (octanol-water)	1.080	(none)		EST
Atmospheric OH Rate Constant	5.35E-11	cm3/molecule-sec	25	EST

3) Descriptors of Structure

InChI: InChI=1S/C6H8N2/c1-5-3-2-4-6(7)8-5/h2-4H,1H3,(H2,7,8)
InChIKey: QUXLCYFNVNNRBE-UHFFFAOYSA-N
Canonical SMILES: CC1=NC(=CC=C1)N
Smiles: n1c(cccc1N)C

4) Production of 2-Amino-6-methylpyridine

This product can be obtained from the amination of 2-Picoline. The reaction should be taken place with the liquid ammonia pass into the reaction tank. Then add the nitric acid high iron and mix points time slowly to join a small piece of sodium metal, add finish and continue to stir 3 h. Then discharge the ammonia and to the reaction liquid is diluted slurry, ammonia liquid sodium. Add the anhydrous xylene to the ammonia sodium, mixing temperature and steam in addition to residual ammonia and add the 2-Picoline to get the 2-Amino-6-methylpyridine (CAS NO.1824-81-3).

5) Uses of 2-Amino-6-methylpyridine

2-Amino-6-methylpyridine (CAS NO.1824-81-3) can be used in the organic synthesis. You can also use it to manufacture photographic developer, dye and drug.