Propitocaine hydrochloride

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1 Kilogram	FOB Price: USD 525.0000

1 Kilogram

FOB Price: USD 525.0000

Propitocaine hydrochloridecas:1786-81-8 1786-81-8 Propitocaine hydrochloride

Prilocaine / pra l ke n/ is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions likeparesthesia. As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia (IVRA).

In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue.

Maximum dosage for dental use: 8.0 mg/kg (2.7 mg/lb), with a maximum dose of 500 mg.

It is given as a combination with the vasoconstrictor epinephrine under the trade name Citanest Forte.

Prilocaine hydrochloride
Identification
Name		Prilocaine hydrochloride
Synonyms		Propitocaine hydrochloride; 2-(Propylamino)-o-propionotoluidide hydrochloride; N-(2-Methylphenyl)-2-(propylamino)-propanamide hydrochloride

Molecular Structure

Molecular Formula		C₁₃H₂₀N₂O^.HCl
Molecular Weight		256.77
CAS Registry Number		1786-81-8
EINECS		217-244-0

Properties

Melting point		167-168 ºC