High quality Silodo...

High quality Silodosin Silodosin Supplier 160970-54-7
High quality Silodosin Silodosin Supplier 160970-54-7

High quality Silodosin Silodosin Supplier 160970-54-7

Min.Order / FOB Price:Get Latest Price

10 Kilogram

FOB Price: USD 2.0000

  • Min.Order :10 Kilogram
  • Purity: 98%
  • Payment Terms : T/T,

Keywords

Silodosin High quality Silodosin cas no:160970-54-7

Quick Details

  • Appearance:White or almost white crystalline powder
  • Application:Aceclofenac is an anti-inflammatory and analgesic drug. Relief of pain and inflammation
  • PackAge:Foil Bag or as Required
  • ProductionCapacity:50|Metric Ton|Day
  • Storage:Storaged in dry, ventilate and cool place, stow away from fire.
  • Transportation:EMS、TNT、DHL、UPS、FEDEX、SF、Wuhan Port、Shanghai Port、Tianjin Port、Guangzhou Port

Superiority:

1,Best Quality:
Our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other countries, and we have got very good feedback from our customers.so you can trust us.
2, Payment method: for example T/T, Westerm Union,other
3, Excellent Service: Best service and after-sales service to all clients.
   1)We will ship the goods within 5days after get your payments.If you want to cancel or change order, please tell me within 24hours after you finish the payment..
   2)We will ship the goods that you order from us by DHL, UPS, TNT and EUB.We will decided to choose which courier depend on different countries.To find the best way to delivery the goods for you.
   3)As usual you can get the goods with in 4-7days.If the goods were lost or not received for other reasons, please contact us immediately.
4,Fast and safe delivery:
Sample Order : As usual you can get the goods within 4-7days. We can send it via HKems, HK Air Post, DHL or other methods.
We have a professional and stable logistics, and we can deliver the package smoothly around 3 to 5 days.
Bulk Order: Shipped via sea or air, it's according to your requirement, delivery time is 7-15days after payment.

We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our customers and principals. With our high-performance teamwork centers and associated production sites for custom synthesis, we ensure effective professional response and offer extensive applications-related consulting and compliance regulation services.

 

Details:

Product Name: Silodosin
Synonyms: (–)-1-(3-Hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-2,3-di-hydro-1H-indole-7-carboxamide;Silodosin;KAD 3213;KMD 3213;Urief;Silodosin API;Silodosin(Rapaflo);(–)-1-(3-Hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-tr
CAS: 160970-54-7
MF: C25H32F3N3O4
MW: 495.53

 

 
Silodosin is a kind of α-adrenergic receptor antagonists developed by Japanese Kissei pharmaceutical company. It has a very good therapeutic efficacy on treating the dysuria related to benign prostatic hyperplasia. The selective effect on urethra of Silodosin is 12 times and 7.4 times as high as that of prazosin and tamsulosin, respectively, which can significantly inhibit norepinephrine-induced contraction of the prostate; it has dose-dependent inhibition bladder activity excitation in the benign prostatic hypertrophy models of rats, and can also improve the pressure threshold of bladder contraction. These data have suggested that, in addition to helping improve bladder function, silodosin is also effective in alleviating the related symptoms associated with benign prostatic hypertrophy. 
Compared with similar drugs such as prazosin and tamsulosin, silodosin has a high selectivity onn theα1A-receptors located in the prostate and bladder neck, while having a low affinity to theα1B-and α1D-receptor. It can block theα1A-receptors in these sites, and relax the smooth muscle, and thus leading to the improvement of urinary flow rate and the alleviation of BPH symptoms.
The selective binding to the α1A-receptor by silodosin has a higher selectivity compared to the binding to the cardiovascular associated receptors α1B, thus maximizing the activity of the target organ as well as minimizing the potential effect on blood pressure.
 
It can be used for treatment of benign prostatic hyperplasia.
 

 

 

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