3-Carboxyphenylboronic acid

Min.Order / FOB Price:Get Latest Price

1 Kilogram	Negotiable

1 Kilogram

Negotiable

Min.Order :1 Kilogram
Purity: ≥98%(HPLC)
Payment Terms : L/C,T/T

Keywords

25487-66-5

Quick Details

Appearance:Similar white powder
Application:intermediates
PackAge:25KG/NET Fiber Drum with double lined plastic bag inside
ProductionCapacity:10|Metric Ton|Year
Storage:Store in a cool, dry area. Keep container tightly closed.
Transportation:NOT RESTRICTED

Superiority:

1. Introduction of 3-Carboxyphenylboronic acid

3-Carboxyphenylboronic acid (CAS NO.25487-66-5) is a similar white powder and commonly used as

Details:

1. Introduction of 3-Carboxyphenylboronic acid

3-Carboxyphenylboronic acid (CAS NO.25487-66-5) is a similar white powder and commonly used as a intermediate. Our product capacity of it is 10 metric ton per year and can provide its ≥98%(HPLC). It is in stock now and can be ordered from 1 kilogram. Its FOB price of this chemical is 0-100000 USD/kilogram. Whereas, we can accept the payment of L/C or T/T.

Our 3-Carboxyphenylboronic acid:

Appearance: Similar white powder
CAS NO.: 25487-66-5
Assay: ≥98%(HPLC)
Formula: C₇H₇BO₄M.W.: 165.94
Feature: Similar white powder, mp 243-247°C
Packaging: 25KG/NET Fiber Drum with double lined plastic bag inside

Package of 3-Carboxyphenylboronic acid

Widely used in Suzuki coupling chemistry. It can be used for synthetic API.

2. Basic information of 3-Carboxyphenylboronic acid

1) Properties:

(1)H-Bond Donor: 3; (2)H-Bond Acceptor: 4; (3)Rotatable Bond Count: 2; (4)Exact Mass: 166.043739; (5)MonoIsotopic Mass: 166.043739; (6)Topological Polar Surface Area: 77.8; (7)Heavy Atom Count: 12; (8)Complexity: 171; (9)Covalently-Bonded Unit Count: 1.

2) Descriptors of Structure

IUPAC Name: 3-boronobenzoic acid
InChI: InChI=1S/C7H7BO4/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4,11-12H,(H,9,10)
InChIKey: DBVFWZMQJQMJCB-UHFFFAOYSA-N
Canonical SMILES: B(C1=CC(=CC=C1)C(=O)O)(O)O

3) Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	2560mg/kg (2560mg/kg)		"Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964Vol. -, Pg. 693, 1964.
rat	LD50	oral	> 3gm/kg (3000mg/kg)		Acta Physiologica Polonica. Vol. 12, Pg. 173, 1961.

4) Application:

3-Carboxyphenylboronic acid (CAS NO.25487-66-5) can react with 3-bromo-pyridine to get 3-pyridin-3-yl-benzoic acid. This reaction which is a kind of Substitution//Suzuki reaction needs reagent aq. Na₂CO₃, catalytic agent Pd(PPh₃)₄ and solvent acetonitrile at temperature of 90 °C. The reaction time of it is 16 hours. The yield of it is 90%.

The detailed steps:

3-Carboxyphenylboronic acid (CAS NO.25487-66-5) can react with 3-bromo-pyridine to get 3-pyridin-3-yl-benzoic acid