3-Methylamino-1-(2-thienyl)-1-propanol

Details:

1. Introduction of 3-Methylamino-1-(2-thienyl)-1-propanol

3-Methylamino-1-(2-thienyl)-1-propanol (CAS NO.116539-55-0) is a similar white to slightly brownish crystalline powder and can be used as a Duloxetine intermediate. Our 3-Methylamino-1-(2-thienyl)-1-propanol can be NLT99.0% and produced 5 metric ton per year.

Other detailed information:

Appearance:  Similar white to slightly brownish crystalline powder
Loss on drying: NMT1.0%
Heavy metals: NMT20ppm
single impurities: NMT0.5%
Total impurities: NMT1.0%
Assay:  NLT99.0%
Synonyms: 3-Methylamino-1-(2-thienyl)-1-propanol; ;(S)-3-MethylaMino-1-(thiophene-2-yl)propan-1-ol
Fomular: C8H13NOS
M.W.: 171.26
Feature: similar white to slightly brownish crystalline powder
Packaging: 25KG/NET Fiber Drum with double lined plastic bag inside



Packaging Details: Fiber Drum Size: diameter 350mm x height 500mm,tare weight: 2.8-2.9kg PE bag: width 600mm x height 900mm xthickness 0.06mm.

2. Basic information of 3-Methylamino-1-(2-thienyl)-1-propanol

1) Properties:

(1)XLogP3-AA: 0.7; (2)H-Bond Donor: 2; (3)H-Bond Acceptor: 3; (4)Rotatable Bond Count: 4; (5)Exact Mass: 171.071785; (6)MonoIsotopic Mass: 171.071785; (7)Topological Polar Surface Area: 60.5; (8)Heavy Atom Count: 11; (9)Complexity: 110; (10)Defined Atom Stereocenter Count: 1; (11)Covalently-Bonded Unit Count: 1; (12)Feature 3D Acceptor Count: 1; (13)Feature 3D Donor Count: 2; (14)Feature 3D Cation Count: 1; (15)Feature 3D Ring Count: 1; (16)Effective Rotor Count: 4; (17)Conformer Sampling RMSD: 0.6.

2) Descriptors of Structure

InChI: InChI=1S/C8H13NOS/c1-9-5-4-7(10)8-3-2-6-11-8/h2-3,6-7,9-10H,4-5H2,1H3/t7-/m0/s1
InChIKey: YEJVVFOJMOHFRL-ZETCQYMHSA-N
Canonical SMILES: CNCCC(C1=CC=CS1)O
Isomeric SMILES: CNCC[C@@H](C1=CC=CS1)O
IUPAC Name: (1S)-3-(methylamino)-1-thiophen-2-ylpropan-1-ol

3) Application

3-Methylamino-1-(2-thienyl)-1-propanol (CAS NO.116539-55-0) is mostly used as a Duloxetine intermediate.