4-(2-Hydroxyethyl)oxyindole

Details:

1. Introduction of 4-(2-Hydroxyethyl)oxyindole

4-(2-Hydroxyethyl)oxyindole (CAS NO.139122-19-3) is a yellow crystalline powder and can be used as a Ropinirole Intermediate. We can supply its NLT99.0% and produce it 5 metric ton per year. It is in stock and can be sent from the beijing port. Whereas, we are glad to receive the payment from the L/C or T/T.

Synonyms: 4-(2-Hydroxyethyl)oxyindole
Fomular: C₁₀H₁₁NO₂
M.W.: 177.20
Feature: Yellow crystalline powder, 148-150°C

Others:

Appearance: Yellow crystalline powder
CAS NO.: 139122-19-3
Loss on drying: NMT0.5%
Residue on ignition: NMT0.2%
Heavy metals: NMT20ppm
Assay:  NLT99.0%

Package:



Packaging Details: Fiber Drum Size: diameter 350mm x height 500mm,tare weight: 2.8-2.9kg PE bag: width 600mm x height 900mm xthickness 0.06mm.

2. Basic information of 4-(2-Hydroxyethyl)oxyindole

1) Properties:

(1)mp: 148-150°C; (2)Storage temp.:  Refrigerator; (3)ACD/LogD (pH 5.5): 0; (4)ACD/LogD (pH 7.4): 0; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 34; (8)ACD/KOC (pH 7.4): 34; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 49.33 ?²; (13)Index of Refraction: 1.6; (14)Molar Refractivity: 48.378 cm³; (15)Molar Volume: 141.378 cm³; (16)Polarizability: 19.179×10^-24cm³; (17)Surface Tension: 52.878 dyne/cm; (18)Density: 1.253 g/cm³; (19)Flash Point: 189.677 °C; (20)Enthalpy of Vaporization: 67.442 kJ/mol; (21)Boiling Point: 390.019 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.

2) Descriptors of Structure

(1)SMILES: OCCc1cccc2NC(=O)Cc12
(2)InChI: InChI=1/C10H11NO2/c12-5-4-7-2-1-3-9-8(7)6-10(13)11-9/h1-3,12H,4-6H2,(H,11,13)
(3)InChIKey: QRTHVOUKWCEPKJ-UHFFFAOYAB
 
It is one kind of Ropinirole intermeidates.