Pramipexole dihydrochloride

Details:

1. Introduction of Pramipexole dihydrochloride

Synonyms: (S)-2-Amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole dihydrochloride
Fomular: C10H17N3S.2HCl
M.W.: 284.25
Feature:  white to off-white powder, 288-290°C

Pramipexole dihydrochloride (CAS NO.104632-25-9) is a white to off-white powder and can be used to produce the drug antiparkinsonian. We can supply its NLT 99.0%(HPLC) and can be manufactured it 5 metric ton per year. Besides, it is in stock and can be deliveried from the beijing port.

Others:

Appearance: white to off-white powder
Loss on drying: NMT 0.5%
Residue on ignition: NMT 0.5%
Heavy metals: NMT 20ppm
Assay: NLT 99.0%(HPLC)
[α]D20: -65~69o

Packaging: 25KG/NET Fiber Drum with double lined plastic bag inside
                 Fiber Drum Size: diameter 350mm x height 500mm,tare weight: 2.8-2.9kg
                 PE bag: width 600mm x height 900mm xthickness 0.06mm

 

2. Basic information of Pramipexole dihydrochloride

1) Properties:

(1)H-Bond Donor: 4; (2)H-Bond Acceptor: 4; (3)Rotatable Bond Count: 3; (4)Tautomer Count: 2; (5)Exact Mass: 283.067674; (6)MonoIsotopic Mass: 283.067674; (7)Topological Polar Surface Area: 79.2; (8)Heavy Atom Count: 16; (9)Complexity: 188; (10)Defined Atom Stereocenter Count: 1; (11)Covalently-Bonded Unit Count: 3.

2) Descriptors of Structure

InChI: InChI=1S/C10H17N3S.2ClH/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8;;/h7,12H,
2-6H2,1H3,(H2,11,13);2*1H/t7-;;/m0../s1
InChIKey: QMNWXHSYPXQFSK-KLXURFKVSA-N
Canonical SMILES: CCCNC1CCC2=C(C1)SC(=N2)N.Cl.Cl
Isomeric SMILES: CCCN[C@H]1CCC2=C(C1)SC(=N2)N.Cl.Cl
IUPAC Name: (6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine;dihydrochloride

3) Usage

Pramipexole dihydrochloride (CAS NO.104632-25-9) can be used as a dopamine-D2-receptor agonist. You can use it to manufacture the antiparkinsonian drug.