Manufacturer supply High Quality Neomycin Sulphate CAS 1405-10-3

Details:

Manufacturer supply High Quality Neomycin Sulphate CAS 1405-10-3

Prouduct name:  Neomycin Sulphate

CAS: 1405-10-3

Appearance: White or yellowish-white powder

 

Content: 99.0%min

 

Product Name

Neomycin sulfate

Synonyms

mycifradin sulfate; o-2,6-diamino-2,6-dideoxy-.beta.-l-idopyranosyl-(1.->3)-o-.beta.-d-ribofuranosyl-(1->5))-o-(2,6-diamino-2,6-dideoxy-.alpha.-d-glucopyranosyl-(1->4))-2-deoxy sulfate

CAS

1405-10-3

EINECS

215-773-1

Molecular formula

C23H48N6O17S

Molecular Weight

712.72

Molecular Structure

 

Physical andChemical Properties

M.P.		>187°C (dec.)
B.P.	1046.1ºC at 760 mmHg
F.P.	586.5ºC
Water Solubility	H2O: 50 mg/mL

 

General Description

white or milk white crystalline powder; odorless or almost odorless; easily soluble in water, slightly soluble in ethanol.

Usage

Neomycin Sulphate is an active pharmaceutical ingredient used as an aminoglycoside antibiotic

Packing

0.5kgs/Al-foil bag 1.0kgs/Al-foil bag

2.0kgs/Al-foil bag 5.0 kgs/Al-foil bag

25.0 kgs/drum or upon customers

Specifications

Items

Standard

Appearance

White or yellowwish-whote powder, odorless or almost hygroscopic.

Identification

A; B; C the positive reaction

Solubility

Very soluble in water, insoluble in acetone, chloroform, ether

Specific optical rotation

+53.5°~59.0°

Acidity of alkalinity

5.0~7.5

Impurity A

≤2.0%

Impurity C

3.0%~15%

Any other impurities

Not more than the area if the principal peak in the chromatogram obtained with RS(B)(5.0%)

Total other impurities

Not more than 3 times the area of the principal peak in the chromatogram obtained with RS(B)(15.0%)

Disregard limit

Area of the principal peak in the chromatogram obtained with RS(C)(1%)

Loss on drying

≤8.0%

Sulphated ash

≤1.0%

Assay

≥680IU/MG(DRY)

Conclusion

The specification conform with BP2010 Edition

Function

1, Neomycin Sulfate Mainly for the treatment of trachoma, conjunctivitis, and so on.

2,Oral administration can be used to:

(1). Neomycin Sulfate can used to Intestinal infection.

(2). Neomycin Sulfate Can also be used as an adjuvant therapy for bowel preparation before colon surgery or hepatic coma.

3,Neomycin should not be used for the treatment of systemic infections.

Mainly for the treatment of trachoma, conjunctivitis, and so on.