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6-Bromoquinoline Basic information |
Product Name: | 6-Bromoquinoline |
Synonyms: | 6-BROMOQUINOLINE;TIMTEC-BB SBB001559;6-bromo-quinolin;Quinoline, 6-bromo-;6-BROMOQUINOLINE 95+%;6-BROMOOQUINOLINE;6-Bromoquinoline ,98%;NSC 3996 |
CAS: | 5332-25-2 |
MF: | C9H6BrN |
MW: | 208.05 |
EINECS: | 206-363-3 |
Product Categories: | blocks;Bromides;Quinolines;Halides;Quinolines, Isoquinolines & Quinoxalines;Quinoline&Isoquinoline;Miscellaneous;Quinoline Derivertives;Aromatics Compounds;Haloquinolines;quinoline;Aromatics;Heterocycles;Quinolines, Isoquinolines & Quinoxalines;Boronic Acid;Heterocyclic Compounds;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;QuinolinesHeterocyclic Building Blocks |
Mol File: | 5332-25-2.mol |
6-Bromoquinoline Chemical Properties |
Melting point | 19°C |
Boiling point | 116 °C / 6mmHg |
density | 1.55 |
refractive index | n20/D 1.663 |
Fp | 19 °C |
storage temp. | Refrigerator |
solubility | Soluble in acetone, acetonitrile, dichloromethane, ethyl acetate and THF. |
CAS DataBase Reference | 5332-25-2(CAS DataBase Reference) |
NIST Chemistry Reference | 6-Bromo quinoline(5332-25-2) |
EPA Substance Registry System | Quinoline, 6-bromo-(5332-25-2) |
Safety Information |
Hazard Codes | Xi,Xn |
Risk Statements | 36/37/38-41-37/38-22-20/21/22 |
Safety Statements | 26-37/39-39-36 |
Hazard Note | Irritant |
TSCA | Yes |
HazardClass | IRRITANT |
6-Bromoquinoline Usage And Synthesis |
Bromoquinoline | There are seven positional isomers of bromoquinoline and their main properties are listed below: |
Application and synthetic method |
3-bromo-quinoline is reacted with mixed acid for generating 3-bromo-5-nitro-quinoline, which heats together with potassium permanganate for being oxidation into 5-bromo-2, 3-pyridine dicarboxylic acid. 6-bromo-quinoline is heated together with nitric acid to generate 6-bromo-8-nitro quinolone with further reaction with potassium permanganate for being oxidized to 2, 3-pyridinedicarboxylic acid. 2-bromo-quinolien can be synthesized through the reaction between 2-hydroxy quinoline and phosphorus pentabromide. Quinoline perbromide is heated at 180 °C for generating 3-bromo-quinoline. From the heating between 4-hydroxy quinoline and phosphorus pentabromide, or from the diazotization reaction via 4-aminoquinoline to generate 4-bromo-quinoline; 5-bromo-quinoline is synthesize by the heating reaction between m-bromo-aniline, glycerol, m-bromo nitrobenzene and concentrated sulfuric acid, or from the diazotization reaction of 5-aminoquinoline. 6-bromo-quinoline can be synthesized from the heating of bromoaniline, glycerol, concentrated sulfuric acid, and p-bromo-nitrobenzene. 7-bromo-quinoline can be synthesized from the diazotization reaction of 7-aminoquinoline. 8-bromo-quinoline can be synthesized from the heating reaction of o-bromo-aniline, glycerol, concentrated sulfuric acid and o-bromo nitrobenzene. application: as organic synthesis reagents. The above information is edited by the Chemicalbook of Dai Xiongfeng. |
Chemical Properties | Thick Oil |
6-Bromoquinoline Preparation Products And Raw materials |
Raw materials | Sodium hydroxide-->Sulfuric acid -->Tetrahydrofuran-->Toluene-->1-Butanol-->Zinc chloride-->Glycerol-->Acrolein-->4-Bromoaniline-->Chloranil-->1-Bromo-4-nitrobenzene |
High purity 6-Bromoquinoline CAS 5332-25-2 with fast delivery
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