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1 Kilogram |
Negotiable |
Isonicotinic hydrazide INAH Isoniazid
Isoniazid is an antibacterial agent used primarily as a tuberculostatic. Target: Antibacterial Isoniazid is a prodrug and must be activated by a bacterial catalase-peroxidase enzyme that in M. tuberculosis is called KatG [1]. KatG couples the isonicotinic acyl with NADH to form isonicotinic acyl-NADH complex. This complex binds tightly to the enoyl-acyl carrier protein reductase known as InhA, thereby blocking the natural enoyl-AcpM substrate and the action of fatty acid synthase. This process inhibits the synthesis of mycolic acid, required for the mycobacterial cell wall. A range of radicals are produced by KatG activation of isoniazid, including nitric oxide, which has also been shown to be important in the action of another antimycobacterial prodrug PA-824 [2, 3]. Isoniazid is bactericidal to rapidly dividing mycobacteria, but is bacteriostatic if the mycobacteria are slow-growing [4].
mycobacteria, but is bacteriostatic if the mycobacteria are slow-growing.
Name |
Isoniazid |
Synonyms |
Isonicotinic acid hydrazide; INAH; Pyridine-4-carbohydrazide |
Brand |
MingQi |
Molecular Formula |
C6H7N3O |
Molecular Weight |
137.14 |
CAS Registry Number |
54-85-3 |
EINECS |
200-214-6 |
Items |
Standard |
Results |
Characters |
A white crystalline powder or colorless crystals |
A white crystalline powder |
Identification |
Conforms |
Conforms |
Melting Point |
170-174°C |
171-172°C |
PH |
6.0-8.0 |
7.1 |
Solution Colour |
Conforms |
Conforms |
Clearness |
Conforms |
Conforms |
Hydrazine and related substances |
Conforms |
Conforms |
Loss on drying |
≤0.5% |
0.11% |
Sulphate ash |
≤0.1% |
0.02% |
Heavy Metals |
≤0.001% |
<0.001% |
Assay |
99.0~101.0% |
99.40% |
Packing |
25kg woven bag packaging, plastic-lined;According to user requirements to provide various types of packaging |
Function:
Antituberculosis It inhibits and kills Mycobacterium tuberculosis. Its biomembrane permeability is good. Because of its good curative effect, low toxicity, low cost, and convenience for oral administration, it is listed as the first choice antituberculosis drug.
Antidepressant Isoniazid is also the first antidepressant drug, but it exits the market because of its hepatotoxicity.
Antibacterial Isoniazid is highly selective for Mycobacterium tuberculosis, strong antibacterial activity, bacteria have bactericidal effect
Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.
Our advantages:
1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.
3,We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.
Items |
Standard |
Results |
Characters |
A white crystalline powder or colorless crystals |
A white crystalline powder |
Identification |
Conforms |
Conforms |
Melting Point |
170-174°C |
171-172°C |
PH |
6.0-8.0 |
7.1 |
Solution Colour |
Conforms |
Conforms |
Clearness |
Conforms |
Conforms |
Hydrazine and related substances |
Conforms |
Conforms |
Loss on drying |
≤0.5% |
0.11% |
Sulphate ash |
≤0.1% |
0.02% |
Heavy Metals |
≤0.001% |
<0.001% |
Assay |
99.0~101.0% |
99.40% |
Packing |
25kg woven bag packaging, plastic-lined;According to user requirements to provide various types of packaging |
Shaanxi Mingqi Chemical Co., Ltd is committed to the development of import and export trade in the production, operation and plant extracts of pharmaceutical raw materials and intermediates. It has trade with other Asian countries and Europe, the Americas and African countries. Important exporters of pharmaceutical chemical raw materials and the world's latest importers of pharmaceutical raw materials.
Shaanxi Mingqi Chemical Co., Ltd has always been adhering to the company to market-oriented, customer-centric, with professional and enterprising team spirit and the company's strong financial strength, to provide customers with fast, high quality and efficient services, and always " To benefit customers "for the purpose.
In the pharmaceutical raw materials and intermediates export business, the company by virtue of years of accumulated experience and high quality and reasonable talent structure, accurate grasp of the market, not only with a number of well-known domestic production enterprises to establish a long-term stable strategic cooperative relations in the global pharmaceutical chemical raw materials And chemical intermediates on the market also won the loyal customer base and a very strong strategic partner, set up a professional image of the outsourcing of pharmaceutical procurement. On the basis of continuing to develop the existing export trade business, the Company has formulated the idea of establishing independent research and development center and constructing the production base of pharmaceutical and chemical products according to the future development trend of the pharmaceutical and chemical industry, and strives to establish the combination of R & D, manufacturing and trade Of the business development model.
While actively expanding their business and creating economic profits, enterprises do not forget their social responsibility, and actively participate in greening trees, poor students and other social activities, and become a tradition for many years, creating a good social benefits.
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