Factory supply High Quality Lactulose Powder CAS 4618-18-2

Details:

Basic Information 

Product name:Lactulose 
Other name:4-O-beta-D-Galactopyranosyl-alpha-D-fructose
Formula:C12H22O11 
Molecular weight:342.30
CAS no:4618-18-2
Melting point :173-178 ºC
Specific Rotation :-47 º (C=5, H2O, 12HR)
Storage conditions:Refrigerator
Water Solubility:76.4 G/100 ML (30 ºC)
Density: 1,32g/cm

Introduction

Lactulose is a synthetic, non-digestible sugar used in the treatment of chronic constipation and hepatic encephalopathy, a complication of liver disease. It is a disaccharide (double-sugar) formed from one molecule each of the simple sugars (monosaccharides) fructose and galactose. Lactulose is not normally present in raw milk, but is a product due to the heat-processes: the more the heat, the more the presence of this substance (from 3.5 mg/l in low temperature pastorized milk to 744 mg/l in in-container sterilized milk).It is produced commercially by isomerization of lactose.

It is broadly classified as an osmotic laxative. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Referance Specification

Usage:

Constipation
Lactulose is used in the treatment of chronic constipation in patients of all ages as a long-term treatment.
Lactulose is used for chronic idiopathic constipation, i.e. chronic constipation occurring without any identifiable cause. This is by far the most common finding.
Lactulose may be used to counter the constipating effects of opioids, and in the symptomatic treatment of hemorrhoids as a stool softener.
The dosage of lactulose for chronic ideopathic constipation is adjusted depending on the constipation severity and desired effect, from stool softening to a strong bowel movement. Dosage is reduced in case of galactosemia as most preparation contain the monosaccharide galactose due to its synthesis process. The dosage for an adult ranges from one to four tablespoons with breakfast and for children, one (five milliliter) teaspoon for each year of age up to age sixteen.

Hyperammonemia

Lactulose is useful in treating hyperammonemia (high blood ammonia). This can be caused by hepatic encephalopathy. Lactulose helps trap the ammonia (NH3) in the colon. It does this by using gut flora to acidify the colon, transforming the freely diffusible ammonia into ammonium (NH4+) which can no longer diffuse back into the blood. It is also useful for preventing hyperammonemia caused as a side effect of administration of valproic acid.
Lactulose for hepatic encephalopathy generally requires oral dosage three or four times a day with episodic diarrhea and constant flatulence almost a certain side effect. People who take lactulose at this level of dosage generally end up wearing an adult diaper and plastic pants for any activities away from home or at night (with a chux pad for the bed) because the diarrhea can occur swiftly and without much warning.

Shaanxi Mingqi Chemical Co., Ltd is committed to the development of import and export trade in the production, operation and plant extracts of pharmaceutical raw materials and intermediates. It has trade with other Asian countries and Europe, the Americas and African countries. Important exporters of pharmaceutical chemical raw materials and the world's latest importers of pharmaceutical raw materials.

    Shaanxi Mingqi Chemical Co., Ltd has always been adhering to the company to market-oriented, customer-centric, with professional and enterprising team spirit and the company's strong financial strength, to provide customers with fast, high quality and efficient services, and always " To benefit customers "for the purpose.

      In the pharmaceutical raw materials and intermediates export business, the company by virtue of years of accumulated experience and high quality and reasonable talent structure, accurate grasp of the market, not only with a number of well-known domestic production enterprises to establish a long-term stable strategic cooperative relations in the global pharmaceutical chemical raw materials And chemical intermediates on the market also won the loyal customer base and a very strong strategic partner, set up a professional image of the outsourcing of pharmaceutical procurement. On the basis of continuing to develop the existing export trade business, the Company has formulated the idea of ??establishing independent research and development center and constructing the production base of pharmaceutical and chemical products according to the future development trend of the pharmaceutical and chemical industry, and strives to establish the combination of R & D, manufacturing and trade Of the business development model.

      While actively expanding their business and creating economic profits, enterprises do not forget their social responsibility, and actively participate in greening trees, poor students and other social activities, and become a tradition for many years, creating a good social benefits.