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High Purity Anti Hypertensive Drugs Irbesartan for Hypertension Treatment,CAS:138402-11-6 Irbesartan CAS 138402-11-6
product Name | Irbesartan |
---|---|
Synonyms | Irbesartan (GMP); 3-butyl-2-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one; 2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE; BMS-186295; AVAPRO; APROVEL; SR-47436; 2-butyl-3-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one |
MolecularFormula | C25H28N6O |
MolecularWeight | 428.53 |
CAS NO | 138402-11-6 |
Density | 1.3g/cm 3 |
Melting point | 180-181°C |
Boiling point | 648.6°C at 760 mmHg |
Refractive index | 1.689 |
Flash point | 346°C |
VapourPressur | 1.05E-16mmHg at 25°C |
Water | NMT 0.5% |
Limit of azide | NMT 10ppm |
Heavy metals | NMT 0.002% |
Appearance | White to Off-white, crystalline powder |
Introduction
Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. As with all angiotensin II receptor antagonists, irbesartan is indicated for the treatment of hypertension. Irbesartan may also delay progression of diabetic nephropathy and is also indicated for the reduction of renal disease progression in patients with type 2 diabetes, hypertension and microalbuminuria (>30 mg/24 hours) or proteinuria (>900 mg/24 hours).
Medical Use
As with all angiotensin II receptor antagonists, irbesartan is indicated for the treatment of hypertension. Irbesartan may also delay progression of diabetic nephropathy and is also indicated for the reduction of renal disease progression in patients with type 2 diabetes, hypertension and microalbuminuria (>30 mg/24 hours) or proteinuria.
Applications
Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
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