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Lorcaserin hydrochloride hemihydrate CAS:856681-05-5 Lorcaserin hydrochloride hemihydrate CAS:856681-05-5
High quality Lorcaserin hydrochloride hemihydrate CAS:856681-05-5
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High quality Lorcaserin hydrochloride hemihydrate CAS:856681-05-5
Product Description
Lorcaserin hydrochloride hemihydrate: (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine hydrochloride hemihydrate
Molecular Structure:
Molecular Formula: 2(C11H14ClN).2(HCl).H2O
Molecular Weight: 482.32
CAS No.: 856681-05-5
Product Analysis
Test Item |
Specifications |
Result |
|
Apperance |
White to off-white crystalline powder |
off-white crystalline powder |
|
(ID) |
IR |
IR spectrum should conforms |
Conforms with standard |
|
Retention Time |
RT under chirality should conforms |
Conforms with standard |
|
Chloride |
It gives a reaction of Chloride |
Positive reaction |
Water |
3.0 ~ 4.5% |
4.04 % |
|
Melting point |
198~202℃ |
198.9~200.2℃ |
|
ROI |
≤0.2% |
0.05% |
|
Heavy Metal |
≤10ppm |
Conforms |
|
Residual Solvent |
Dichloromethane ≤0.06% |
0.042% |
|
|
Acetone ≤0.5% |
Undetected |
|
|
Ethyl acetate ≤0.5% |
0.32% |
|
Related substances |
Single Impurity ≤ 0.5% |
0.04% |
|
|
Total Impurity ≤1.0% |
0.04% |
|
Enantionmer |
Not more than 2% |
0.05% |
|
Purity (By HPLC) |
Not less than 99.0% |
99.96% |
|
Conclusion: Complies with all requirements of the quality standards of R-Lorcaserin.HCL.1/2 H2O |
Function and Application
Lorcaserin hydrochloride is an agonist of the 5-HT2C receptor and shows effectiveness at reducing obesity in animal models and humans. Further, 5-HT2C receptor is recognized as a well-accepted receptor target for the treatment of obesity, psychiatric, and other disorders.
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