Zolmitriptan Zolmitriptan high purity (4R)-4-[[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one
Introduction
Product: Zolmitriptan
CAS NO.: 139264-17-8
Purity: >99%
Appearance: white to off-white crystalline powder
Functions: Zolmitriptan (311C90) is a dual action 5-HT1D/1B receptor agonist originally synthesized by Glaxo Wellcome (GM), but subsequently developed by AstraZeneca for migraine. It acts peripherally in the brain by constricting cerebral blood vessels, and centrally at the trigeminal nucleus.
Function
Zolmitriptan (311C90) is a dual action 5-HT1D/1B receptor agonist originally synthesized by Glaxo Wellcome (GM), but subsequently developed by AstraZeneca for migraine. It acts peripherally in the brain by constricting cerebral blood vessels, and centrally at the trigeminal nucleus.
Specification
Test Items |
Specification |
Results |
Description |
White to off white crystalline powder |
Comply |
Melting point |
166-170°C |
167.3-168.1°C |
Identification |
Positive reaction |
Positive reaction |
Related substances |
≤1.0% |
0.16% |
Loss on drying |
≤0.5% |
0.06% |
Residue on ignition |
≤0.1% |
0.02% |
Chloride |
≤0.014% |
<0.014 |
Heavy Metals |
≤20ppm |
<20ppm |
Clarity of solution |
Conform to standard |
Complies |
Microbial Limit |
≤20ppm |
<20ppm |
Assay |
≥99.0% |
99.12% |
Kono Chem Co.,Ltd is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries.
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