CasNo.123997-26-2,CAS:123997-26-2 Eprinomectin,(123997-26-2) Suppliers

1 Kilogram	Negotiable

Min.Order :1 Kilogram
Purity: 99.5%
Payment Terms : T/T,Other

Keywords

Eprinomectin Eprinomectin high purity (4''R)-4''-(ACETYLAMINO)-4''-DEOXY-AVERMECTIN B1

Quick Details

Appearance:White powder
Application:Pharmaceutical
PackAge:according to customers' requirements
ProductionCapacity:100|Kilogram|Week
Storage:store in cool and dry
Transportation:by sea or by air

Superiority:

Introduction

Product Name: EprinomectinOrigin:It is a semi-synthesized product of fermented Avermectin B1.Chemical name: 4"-epi-4"-deoxy-acetylaminoavermectin B1Formula and molecular weight: B1a C5OH75NO14=913 B1b C49H73NO14=899Assay: Based on drying, it contains of B1 not less than 90%.Character: The product is white or light yellow crystalline powder.Its melting point is 161-166°C.The product is soluble in methanol, ethanol and ethyl acetate, not soluble in water.Usage: It is not only a broad spectrum and the most efficacious antiparasite drug of Averrmectin kind, but also one of this kind of drugs with the lowest distribution coefficients in milk. Tests show that the product, administered as 0.2mg/kg body weight, can effectively prevent and treat internal and external parasites of cattle and sheep. After administered to lactating cattle, the concentration ratio in milk to in plasma is less than 0.2. The residue amount of the drug in milk is low, so it does not need withdrawal period when administered to lactating cow; the residue amount in muscle is low, so there is also no withdrawal period in beef cattle.Storage: Keep closed and store away from light in a cool and dry place.

Application

Eprinomectin is a mixture of eprinomectins B1a and B1b in a 9:1 ratio, produced from a mixture of avermectin B1a and B1b. Eprinomectin is used commercially as a topical endectocide (insecticide, miticide and nematocide) for cattle, including lactating dairy cows. Like all avermectins and milbemycins, eprinomectin acts by binding to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite, mite or insect.

It is not only a broad spectrum and the most efficacious pesticide of Avermectin kind, but also one of the lowest distribution coefficient of this kind in milk. Trials show that the product with the concentration of 0.1mg/kg or 0.05mg/kg can efficaciously prevent seven kinds of nematodes parasitic on large intestine, small intestine and stomach of cattle and sheep, the efficacy is shown as at least 97%. When it is used to cow in milk, concentration ratio in milk to in plasma is not more than 0.2. It has the advantage over other drugs against nematodes parasitic on cow during milking.

Specification

Tests	Specifications	Test results
Description	White or pale yellow crystalline powder	Complies
Ingredient B1 B1a	≥90.0% ≥90.0%	96.02% 92.92%
Moisture	≤1.0%	0.5%
Non-dissolve in acetone	≤0.1%	0.02%
Loss on drying	≤4.0%	1.8%
Avermectin	≤0.5%	0.2%
Residue on ignition	≤0.1%	0.01%
Heavy metals	≤20ppm	Complies
Arsenic salt	≤2ppm	Complies

Details:

Kono Chem Co.,Ltd is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries.

The botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by Pioneer. They include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis.

With our phytopharmaceutical background and knowledge through experience, PIONEER can also provide a wide range of analytical services and reference substances to our clients. In addition, We also manufacture pharmaceutical raw materials of nucleotide species, mainly including as below: SAM-e Tosylate Disulfate; SAM-e 1,4-Butanedisulfonate; Polycytidylic Acid; Polyinosinic Acid; Adenosine Triphosphate Disodium; and Cytidine Triphosphate Disodium; these items are our strongest advantage in China. Meanwhile, we can do custom made pharmaceutical ingredients depending on our professional experts in the pharmaceutical and chemistry industry.

Recently, Kono Chem has been working hard on the research and development of new cardiovascular and anesthesia drugs, we have got good achievements; moreover, we also offer natural anticancer drugs and other pharmaceutical intermediates. As a GMP standardized manufacturer, our products can meet or even exceed the standards of CP2010, USP32, BP2005 and EP4. Presently, 80% and above of our products have been well-recognized in dozens of countries and regions, such as USA, EU, South America and Southeast Asia. There are experienced technicians working for our institutes now, all of them are skilled. Pioneer is looking forward to cooperating with friends all over the world for getting collaborative development; we are willing to work with you to develop new drugs and expand new business, let's work together for bright future.