Probenecid Probenecid high purity 4-[(Dipropylamino)sulfonyl]benzoic acid
CAS No.:57-66-9
Other Names:4-[(dipropylamino)sulfonyl]-benzoicaci acid
MF:C13H19NO4S
EINECS No.:200-344-3
Place of Origin:Anhui, China (Mainland)
Type:Antineoplastic Agents, Auxiliaries and Other Medicinal Chemicals, Electrolyte Balance and Dialysis Agents, Respiratory System Agents
Grade Standard:Medicine Grade
Usage:Animal Pharmaceuticals
Brand Name:JOYE
Purity:98.5%
Appearance:White crystalline powder.
Molecular Weight:285.36
Specification
Item |
Specifications |
Results |
Appearance |
White crystalline powder |
Complies |
Identification |
IR, UV |
Complies |
Melting point |
198~200℃ |
198.5~199.3℃ |
Acidity |
-- |
Complies |
Related Substances |
Single: ≤0.5% |
Complies |
Total: ≤2.0% |
-- |
|
Selenium |
≤0.003% |
Complies |
Loss on drying |
≤0.5% |
0.26% |
Sulfated ash |
≤0.1% |
0.06% |
organic volatile impurities |
-- |
Complies |
Heavy metals |
≤20ppm |
Complies |
Assay(on dried basis) |
98.0~101.0% |
Conclusion |
The results conforms with USP32 standards |
Application
Probenecid is a kind of anti-gout drug. The product is organic acid, strongly fat-soluble, self-discharge from tubular secretion, very easily to be absorbed back. Therefore, in the presence of probenecid, the transfer of some organic acids in the tubular body will be inhibited, reducing the excretion of other organic acids. Thereby, it is used to treat chronic gout with being safe and effective. It has no effects on acute gout pain and inflammation and can’t be applied to acute gout.
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