LH-RH LEUPROLIDE

LH-RH LEUPROLIDE

LH-RH LEUPROLIDE

Min.Order / FOB Price:Get Latest Price

100 Gram

Negotiable

  • Min.Order :100 Gram
  • Purity: 99%
  • Payment Terms : L/C,T/T,

Keywords

Leuprorelin Leuprolide 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide

Quick Details

  • Appearance:White powder
  • Application:Pharmaceutical intermediates
  • PackAge:in aluminium foil bag
  • ProductionCapacity:1000|Kilogram|Month
  • Storage:Room temperature
  • Transportation:By sea, air or express

Superiority:

Chemical properties Fluffy solid. [α] D23-31.7 ° (C = 1, 1% acetic acid).
(GHRH) and follicle stimulating hormone (FSH), regulate the secretion of gonadotropin, improve the serum concentration of testosterone and dihydrotestosterone, and increase the serum concentration of testosterone and dihydrotestosterone, So as to achieve the function of the treatment of reproductive system diseases. For the treatment of prostate cancer, uterine fibroids, ovarian cysts, breast cancer and children with cryptorchidism and so on.
Use of peptide raw materials
Production method Phenol and phosgene reaction, the formation of phenyl chloroformate, and tert-butanol reaction, the formation of tert-butoxyphenyl phenyl ester, followed by hydrazine reaction, and then nitrosation to produce tert-butyl azide, and then bright ammonia Acid reaction to obtain leucine side chain.
The proline side chain can also be obtained.
The serine is reacted with benzyl chloride to protect the hydroxyl group and react with t-butyl azide to give the serine side chain.
Similar to serine, side chains of tyrosine and histidine can be obtained.
Tert-butyl azide and tryptophan, and then reacted with 2,4,6-trimethoxybenzenesulfonyl chloride to give the tryptophan side chain.
Tert-butyl azanoate and arginine, and then p-toluenesulfonyl chloride reaction, to obtain arginine side chain.
After the above-mentioned side chain is obtained, the peptide is further reacted with ethylamine, followed by reaction with ethylamine, and then deprotecting or hydrogenolysis to remove the support base.

Details:

Henan Tianfu Chemical Co., Ltd is a high-tech enterprise, specializing in pharmaceutical intermediates, located in Zhengzhou High-tech Development Zone. We passed ISO 9001:2008 ub 2009, and won "High-tech Enterprise" by provincial government in 2013. Tianfu specializes in manufacuturing intermediates in areas such as Antitumor, Cardiocascular, central nervous system, diabetes, etc. Tianfu have established an efficient quality control system, owing standardization workshop. Also corportaes with Zhengzhou University, Henan University to establish an innovation practice base to omprove the innovatin ability.
 
Tianfu always adheres to the principle of "Live on High Quality" and puts the customer's interests first. Tianfu products have been exported to Europe and the United States, Japan, Korea, India and Latin America markets. Look forward to the future, Tianfu will keep improving the innovation ability to offer better products and service for more and more customers.
 

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