CasNo.112809-51-5,Letrozole Anti Estrogen Letrozole for Treating Breast Cancer CAS NO.112809-51-5,(112809-51-5) Suppliers

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Purity: 99%
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Letrozole Letrozole 112809-51-5 112809-51-5

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Appearance:crystal, powder
Application:Pharmaceutical intermediates
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Details:

Letrozole

Detail:

CAS : 112809-51-5
Purity:99%
Appearance:White or light yellow crystal
Molecular Formula: C17H11N5
Molecular Weight: 285.31
Package:1/foil bag
Usage: Used as API in Treatment of breast disease.

Description:

Letrozole is an anti-estrogen of the Aromatase Inhibitor family and is one of the most potent and powerfully effective of all AI's.It was first developed in an effort to combat breast cancer in post-menopausal women.Letrozole is an oral aromatase inhibitor which is a non-steroidal drug. Letrozole treats hormonally responsive breast cancer after the surgery in females past menopause. It belongs to the class of drugs known as Aromatase inhibitors and Hormones antineoplastics.It acts by decreasing the quantity of estrogen synthesized in the body.And it is one of the most commonly used anti-estrogens among steroid users during steroid use to combat possible estrogenic related side effects. It is so effective as an anti-estrogen in this regard many anabolic steroids have effectively reversed gynecomastia symptoms with Letrozole.

Applications:

Letrozole is used treat early breast cancer in women who have experienced menopause and who have had other treatments, such as radiation or surgery to remove the tumor.In fact,it would prove to be virtually identical to the already popular AI in Arimidex .Letrozole is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen produced by the body. This can slow or stop the growth of some types of breast cancer cells that need estrogen to grow.

Letrozole is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body.

COA:

Tests	Specifications	Results
Appearance	White or off-white crystaline powder	White Crystalline powder
Solubility	Soluble in Chloroform; Soluble in ethanol when heated	Conform
ldentification	(1)Maximum absorption in wavelength of 240 nm Minimum absorption in wavelength of 215 nm	Conform Conform
	(2)Infrared spectrum should be in accordance the dominant peak of contrast	In accordance with the dominant peak of contrast
Melting points	182ºC-184ºC	182ºC
Related substances	≤0.5%	0.3%
Single impurity	≤0.3%	0.2%
Loss on drying	≤1.0%	0.8%
[Assay]	≥98.0%	99.2%
Conclusion	Conforms Specifications of Enterprise Standard.