3-(2-(4-(6-fluoro-1...

3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-one

3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-2-methyl-4h-pyrido[1,2-a]pyrimidin-4-one

Min.Order / FOB Price:Get Latest Price

100 Gram

Negotiable

  • Min.Order :100 Gram
  • Purity: 99%
  • Payment Terms : L/C,T/T,

Keywords

RISPERIDAL RISPERIDAL RISPERIDONE

Quick Details

  • Appearance:White powder
  • Application: Pharmaceutical intermediates
  • PackAge:in aluminium foil bag
  • ProductionCapacity:1000|Kilogram|Week
  • Storage:Room temperature
  • Transportation:BY SEA, AIR OR EXPRESS

Superiority:

Risperidone properties
Melting point 170 ° C
Flash point 9 ℃
Storage conditions Room temp
Solubility DMSO: ≥5 mg / mL
Color white to off-white
CAS database 106266-06-2 (CAS DataBase Reference)
 
Chemical properties from dimethylformamide - isopropanol crystals, melting point 170.0 ℃. Acute toxicity LD50 male, female mice, male and female rats, male and female dogs (mg / kg): 29.7,26.9,34.3,35.4,14.1,18.3 intravenous; 82.1,63.1,113,56.6,18.3,18.3 oral.
The use of 5HT2 receptor and D2 receptor antagonism. For acute and chronic schizophrenia.
Use of anti-mental disorders
Production method 4-formyl chloride-1-acetyl piperidine and m-difluorobenzene in the aluminum chloride catalyst, the acylation, and then hydrochloric acid hydrolysis on the piperidine ring acetylation, and hydroxylamine reaction and then alkali Catalyzed cyclization to give benzisoxazole derivatives. 4.4 parts of the isoxazole derivative, 5.3 parts of 3-chloroethyl-2-methyl-4H-pyrido [1,2-α] pyrimidin-4-one hydrochloride, 8 parts of sodium carbonate and 0.1 part of potassium iodide , In dimethylformamide, heated at 85-90 ° C, risperidone, yield 46%.

Details:

Henan Tianfu Chemical Co., Ltd is a high-tech enterprise, specializing in pharmaceutical intermediates, located in Zhengzhou High-tech Development Zone. We passed ISO 9001:2008 ub 2009, and won "High-tech Enterprise" by provincial government in 2013. Tianfu specializes in manufacuturing intermediates in areas such as Antitumor, Cardiocascular, central nervous system, diabetes, etc. Tianfu have established an efficient quality control system, owing standardization workshop. Also corportaes with Zhengzhou University, Henan University to establish an innovation practice base to omprove the innovatin ability.
 
Tianfu always adheres to the principle of "Live on High Quality" and puts the customer's interests first. Tianfu products have been exported to Europe and the United States, Japan, Korea, India and Latin America markets. Look forward to the future, Tianfu will keep improving the innovation ability to offer better products and service for more and more customers.
 

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