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171596-29-5 sildenafil citrate 171596-29-5 sildenafil citrate 98% 171596-29-5 White powder
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Detail
sildenafil citrate
Synonyms:Sildenafil citrate;piperazine;viagra;generic viagra
CAS:171599-83-0
MF:C28H38N6O11S
MW:666.7
Appearance:White Solid Powder
Description
Sildenafil citrate is the raw material of Viagra, viagra treats erectile dys function and works by relaxing muscles and increases blood flow to particular areas of the body (in this case, the penis, specifically). Its effects last up to four hours. The most common side effects of Viagra are headache, facial flushing, and upset stomach. Rarely, blurred vision, or sensitivity to light may briefly occur.
As well as treating impotence, Sildenafil Citrate can also be effective in treating Pulmonary Arterial Hypertension (PAH). Similarly to how it acts to relax muscles of the penis, it relaxes arterial walls; therefore, reducing resistance and pressure in the arteries.
Sildenafil Citrate is solely active in relaxing muscles and increasing blood flow to the heart, lungs and penis due to PDE-5, yet vasodilation is not increased in other parts of the body.
Application
In 16 separate 4-24 week trials of men (over 18 years old) who suffered from impotence for longer than 6 months, dosages between 10-200 mgs were administered. Significant improvements in erectile function, including frequency of penetration as well as erection duration post penetration, were reported with Sildenfil treatment compared to the placebo group.
Erections were improved in 72% of the Viagra group verses 18% of the placebo group. In all cases effects were dependant upon dosage and improvement was the greatest when dosage exceeded 100 mgs. Responses were decreased by 40-60% in patients suffering from diabetes and prostatectomy, respectively. Withdrawal rates were less than 5% related to negative side effects and limited response rates
Specification
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