TIANFU CHEM--RETAPA...

TIANFU CHEM--RETAPAMULIN

TIANFU CHEM--RETAPAMULIN

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1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 98%
  • Payment Terms : L/C,T/T,,MoneyGram

Keywords

RETAPAMULIN 224452-66-8 RETAPAMULIN

Quick Details

  • Appearance:White to offwhite crystalline powder
  • Application:INTERMEDIATE
  • PackAge:bottle/drum or customer's request
  • ProductionCapacity:100|Kilogram|Month
  • Storage:N/A
  • Transportation:BY AIR, EXPRESS. OR SEA

Superiority:

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:

 

1.Noble Metal Catalysts (Pt.Pd...)

2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)

3.OLED intermediates (Fluorene,Carbazole,Boric acid...)

4.Customs Synthesis

 

Our advantage:

 

1. Higest quality and good package

2.Fast delivery

3.Better payment term

4.Fast response to customer  within 6 hours

5.Good business credit in Europe ,US ,Japan ,Korea

 

Anyway ,if you need any chemicals from China ,Henan Tianfu can help you

Details:

Product Name: RETAPAMULIN
Synonyms: RETAPAMULIN;Rebapamulin;SB-275833;RetapaMulin (SB-275833);(3aS,4R,5S,6S,8R,9R,9aR,10R)-2-(exo-8-Methyl-8-azabicyclo[3.2.1]octan-3-ylsulfanyl)acetic acid 5-hydroxy-4,6,9,10-tetraMethyl-1-oxo-6-vinylperhydro-3a,9-propanocyclopentacycloocten-8-yl ester;RetapaMulin API;tetapaMulin;(1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetraMethyl-9-oxotricyclo[5.4.3.0^{1,8}]tetradecan-6-yl 2-{[(1R,3S,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl]sulfanyl}acetate
CAS: 224452-66-8
MF: C30H47NO4S
MW: 517.77
EINECS:
Product Categories: API, Antibiotics;Inhibitors
Mol File: 224452-66-8.mol
RETAPAMULIN Structure
RETAPAMULIN Chemical Properties
CAS DataBase Reference 224452-66-8(CAS DataBase Reference)
Safety Information
MSDS Information
RETAPAMULIN Usage And Synthesis
Uses Retapamulin is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with Kd of 3 nM
Uses Retapamulin is a semi-synthetic pleuormutilin prepared by reacting pleuromutilin tosylate with tropine-3-thiol to give a more hydrophobic analogue with a tertiary amine. This enables formulation as a stable hydrochloride salt. Retapamulin is a broad spectrum antibiotic with no cross resistance to existing antibiotic classes, and is the first pleuromutilin approved for human use. Like all the pleuromutilins, retapamulin inhibits protein synthesis by binding to domain V of 23S rRNA.
Uses A broad spectrum antibiotic with no cross resistance to existing classes
Uses Retapamulin is a semi-synthetic pleuromutilin prepared by reacting pleuromutilin tosylate with tropine-3-thiol to give a more hydrophobic analogue with a tertiary amine. This enables formulation as a stable hydrochloride salt. Retapamulin is a broad spectrum antibiotic with no cross resistance to existing antibiotic classes, and is the first pleuromutilin approved for human use. Like all the pleuromutilins, retapamulin inhibits protein synthesis by binding to domain V of 23S rRNA.

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