Reserpine high purity Reserpine factory supply Reserpine
Reserpine Chemical Properties |
Melting point | ~265 °C (dec.) |
alpha | D23 -118° (CHCl3); D26 -164° (c = 0.96 in pyridine); D26 -168° (c = 0.624 in DMF) |
refractive index | 177 ° (C=1, DMF) |
Fp | 22℃ |
storage temp. | 2-8°C |
pka | 6.6(at 25℃) |
Water Solubility | Soluble in water. |
Merck | 14,8145 |
BRN | 102014 |
Stability: | Stable, but darkens slowly in light. Combustible. Incompatible with strong acids, reducing agents, oxidizing agents. |
NIST Chemistry Reference | Reserpine(50-55-5) |
EPA Substance Registry System | Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[(3,4,5- trimethoxybenzoyl)oxy]-, methyl ester, (3.beta.,16.beta.,17.alpha., 18.beta.,20.alpha.)-(50-55-5) |
Safety Information |
Hazard Codes | Xn,Xi |
Risk Statements | 22-67-36-10 |
Safety Statements | 22-36/37/39-26 |
RIDADR | 3077 |
WGK Germany | 3 |
RTECS | ZG0350000 |
F | 10-23 |
TSCA | Yes |
PackingGroup | II |
Hazardous Substances Data | 50-55-5(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
ACROS | English |
SigmaAldrich | English |
ALFA | English |
Reserpine Usage And Synthesis |
Chemical Properties | off-white crystalline powder |
Uses | An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive. |
Uses | An inhibitor of transport of biogenic amines into adrenal chromaffin granules |
Definition | ChEBI: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. |
General Description | White or cream to slightly yellow crystals or crystalline powder. Odorless with a bitter taste. |
Air & Water Reactions | Insoluble in water. Reacts slowly with air and water. Darkens slowly on exposure to light. |
Reactivity Profile | Reserpine is a weak base and can form salts with strong acids. Incompatible with oxidizing agents and reducing agents. |
Fire Hazard | Flash point data for Reserpine are not available; however, Reserpine is probably combustible. |
Biological Activity | Binds the vesicular monoamine transporter (VMAT2) and inhibits transport of biogenic amines into adrenal chromaffin granules and synaptic vesicles. Causes depletion of biogenic amine stores. Antihypertensive and antipsychotic. |
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