high quality Pimari...

high quality Pimaricin

high quality Pimaricin

Min.Order / FOB Price:Get Latest Price

1 Gram

FOB Price: USD 1.0000

  • Min.Order :1 Gram
  • Purity: 99%
  • Payment Terms : L/C,T/T,

Keywords

Pimaricin high purity Pimaricin factory supply Pimaricin

Quick Details

  • Appearance:Colorless to light yellow liquid
  • Application:Used in a base-free iridium-catalyzed direct alkylation of active methylene compounds with alcohols.1
  • PackAge:as you requested
  • ProductionCapacity:10|Kilogram|Day
  • Storage:room temperature
  • Transportation:by courier

Superiority:

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:
 
1.Noble Metal Catalysts (Pt.Pd...)
2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)
3.OLED intermediates (Fluorene,Carbazole,Boric acid...)
4.Customs Synthesis
 
Our advantage:
 
1. Higest quality and good package 
2.Fast delivery 
3.Better payment term 
4.Fast response to customer  within 6 hours 
5.Good business credit in Europe ,US ,Japan ,Korea 
 
Anyway ,if you need any chemicals from China ,Henan Tianfu can help you

Details:

 
Pimaricin Chemical Properties
Melting point  2000C (dec)
Boiling point  952℃
alpha  D20 +278° (c = 1 in CH3COOH)
density  1.0 g/mL at 20 °C(lit.)
Fp  >110°(230°F)
storage temp.  2-8°C
solubility  Soluble in DMSO
form  aqueous suspension
Sensitive  Light Sensitive
Merck  13,6453
Stability: Light sensitive
 
Safety Information
Hazard Codes  Xn
Risk Statements  22
Safety Statements  24/25-36
WGK Germany  2
RTECS  TK3325000
F  8-10
MSDS Information
Provider Language
Pimaricin English
SigmaAldrich English
 
Pimaricin Usage And Synthesis
Description Pimaricin (also known as natamycin, INN) belongs to a naturally occurring antifungal agent produced through the fermentation of the bacterium Streptomyces natalensis. It is a kind of macrolide polyene antifungal used for the treatment of fungal keratitis, which is a kind of eye infection. In medical field, it can be used for the treatment of various kind of fungal infections caused by Candida, Aspergillus, Cephalosporium, Fusarium, and Penicillium. In food industry, it can be used as a natural preservative to prevent fungal outgrowth. Its mechanism of action is through binding to the ergosterol in the plasma membrane of fungi, inhibiting the process of ergosterol-dependent fusion of vacuoles and membrane fusion, further inhibiting the fungal growth. It also inhibit the transport of amino acid and glucose through inhibiting membrane transport proteins. 
References #
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Chemical Properties White to Off-White Solid
Uses Polyene antifungal antibiotic
Uses analgesic, antimigraine
Uses Pimaricin is a macrocyclic tetraene originally isolated from Streptomyces natalensis in 1957. Pimaricin exhibits broad spectrum antifungal activity against yeast and filamentous fungi by binding specifically to ergosterol to block fungal growth. Unlike the related polyenes, nystatin and filipin, pimaricin does not change the permeability of the plasma membrane. Pimaricin is used in the food industry for surface treatment of cheeses as a mould inhibitor.

 

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