Iodixanol Properties
Melting point 262-267 ° C (dec.)
The density is 1.266 ± 0.003
Refractive index n 1.4128 ± 0.0003
Storage conditions
Application and synthesis of iodixanol
Chemical properties of melting point 240 ~ 250 ℃. Dissolved in water. Viscosity (37 ° C) 11.1 mPa · s; pH 7.2 ~ 7.6 (C = 320mgI / m1). 50% aqueous solution (W / V): Viscosity 8.3 mPa · s; n1.4128 ± 0.0003; d1.266 ± 0.003. Acute toxicity LD50 mice (mg / kg): 21 Intravenous injection.
Use Non-ionic X-ray photographic agent.
Use X-ray contrast agent. For cardiovascular angiography in adults, cerebral angiography (conventional with i.a. DSA), peripheral arteriography (conventional with i.a. DSA), abdominal angiography (i.a. DSA), urography, venography, and CT-enhancement.
Production method Compound (I) and 1,3-dichloro-2-propanol condensation, that iodixanol.